Protein Info for mRNA_5201 in Rhodosporidium toruloides IFO0880

Name: 13569
Annotation: K02304 MET8 precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 327 transmembrane" amino acids 302 to 324 (23 residues), see Phobius details PF13241: NAD_binding_7" amino acids 24 to 157 (134 residues), 81.1 bits, see alignment E=1.1e-26 TIGR01470: siroheme synthase, N-terminal domain" amino acids 27 to 225 (199 residues), 72.2 bits, see alignment E=2.4e-24 PF14824: Sirohm_synth_M" amino acids 161 to 187 (27 residues), 43.2 bits, see alignment (E = 3.2e-15) PF14823: Sirohm_synth_C" amino acids 190 to 257 (68 residues), 69.6 bits, see alignment E=2.2e-23

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (327 amino acids)

>mRNA_5201 K02304 MET8 precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase (Rhodosporidium toruloides IFO0880)
MSSPSSASTPSSYPAPQPTNSLLLAYQVQTRTILLAGGGPVAASRLYHLLCARPKRLVLF
APDNEDIDDEFRWRVEGESEEAKKGREGIEIEWRKQEFDPTQNKEDLALLDGDEIDMVLT
AIPNPTLSTEICRLCRTRRTPVNVADVPPECDFYFGSVLRRGSLGVMVSTQGKGPRVAAR
IRRKLERAIPENAGEAIENVGQLRKGLREVEKGTGKEAIERRMGWMIRVSDRWSLAQLGE
MDERMRNEVLAGWEKDEARGYWDVNRGKYGGLGWLASFASRLGVGTCPVVKDPDGSAARC
PFVMGSTGFVLGAATAGAVAAVWMRRQ