Protein Info for mRNA_5258 in Rhodosporidium toruloides IFO0880

Name: 13626
Annotation: KOG0538 Glycolate oxidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 434 PF01070: FMN_dh" amino acids 45 to 422 (378 residues), 312.7 bits, see alignment E=3.1e-97 PF01645: Glu_synthase" amino acids 317 to 377 (61 residues), 22.5 bits, see alignment E=6.2e-09

Best Hits

Predicted SEED Role

"L-lactate dehydrogenase (EC 1.1.2.3)" in subsystem L-rhamnose utilization or Lactate utilization or Respiratory dehydrogenases 1 (EC 1.1.2.3)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.1.2.3

Use Curated BLAST to search for 1.1.2.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (434 amino acids)

>mRNA_5258 KOG0538 Glycolate oxidase (Rhodosporidium toruloides IFO0880)
MNKDDLPPRSTPTYALYQREIFLDGATKGKLPEFNTDPDEMENVAKETLSKGGWLYASSN
AGVSWTHRANREAFYRWRIIPRMLVDTNQRDMSCTLKLGKYEWKFDAPLGFAPIGINKIY
HPLGEFNAAKVAGELNLAYALSTAGSQPISEVARVNNEGYAQAGRSRVHGAEKGRFFQLY
WPPNDELTVSLLRDAHENGYSACILTLDTWQLAWRHGDISAANYAFYRGIGHDLGKANPV
FQRMCREKGITDLNSPEAGQYWIDLVWHGRPWSWEQLPWVIKQWQEISGGKPFVLKGIQS
VADAKRAAETEGVDGIVVSNHAGRQVDGAIASLDALKLIIDAGVGEKITVMFDSGIRSAA
DIFKALALGAKFVFCGRPWVYGMSINGETGVRHVMRGLLAEFDILLEVAGYRNLMEINRD
ALVYVPEATLPAKL