Protein Info for mRNA_5272 in Rhodosporidium toruloides IFO0880

Name: 13640
Annotation: K02731 PSMA7 20S proteasome subunit alpha 4

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 284 PF10584: Proteasome_A_N" amino acids 4 to 26 (23 residues), 43.9 bits, see alignment (E = 1.5e-15) PF00227: Proteasome" amino acids 27 to 210 (184 residues), 202.6 bits, see alignment E=4.5e-64

Best Hits

Swiss-Prot: 63% identical to PSA7_CARAU: Proteasome subunit alpha type-7 (psma7) from Carassius auratus

KEGG orthology group: K02731, 20S proteasome subunit alpha 4 [EC: 3.4.25.1] (inferred from 78% identity to lbc:LACBIDRAFT_189495)

Predicted SEED Role

"proteasome subunit alpha4 (EC 3.4.25.1)" in subsystem Proteasome eukaryotic (EC 3.4.25.1)

Isozymes

Compare fitness of predicted isozymes for: 3.4.25.1

Use Curated BLAST to search for 3.4.25.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (284 amino acids)

>mRNA_5272 K02731 PSMA7 20S proteasome subunit alpha 4 (Rhodosporidium toruloides IFO0880)
MSRYDTALTTFAPDGHLFQVDYALEAVRKGTCAVGVRGKECVILAVEKKSVLQLQDPRTV
RKTAMLDDHVCLGFAGLTADARILIDKARIECQSHRLTVEDPVSVEYITRHIAGIQQRYT
QSGGVRPFGVSCLLIGFDHDDPRPRLYLTEPSGIFSAWKANAIGRSSKTVREFLEKNWKA
DMTKDETVQLAVKSLLEVVQTGAKNIDLAVMDGFGSVRNLTQDELAAVVEQIEKDKEAEA
ERKRSRLAQAAASRDAMISGGGLGDGAEGTGAVTAEEEAGAGEV