Protein Info for mRNA_5301 in Rhodosporidium toruloides IFO0880

Name: 13669
Annotation: K13950 pabAB para-aminobenzoate synthetase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 776 TIGR00566: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase" amino acids 13 to 229 (217 residues), 147 bits, see alignment E=2.8e-47 PF00117: GATase" amino acids 64 to 229 (166 residues), 110.2 bits, see alignment E=2.2e-35 PF07722: Peptidase_C26" amino acids 102 to 213 (112 residues), 40.2 bits, see alignment E=6.6e-14 PF00425: Chorismate_bind" amino acids 502 to 766 (265 residues), 279.1 bits, see alignment E=7.9e-87

Best Hits

Predicted SEED Role

"Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) / Para-aminobenzoate synthase, aminase component (EC 2.6.1.85)" in subsystem Chorismate: Intermediate for synthesis of PAPA antibiotics, PABA, anthranilate, 3-hydroxyanthranilate and more. or Folate Biosynthesis or Tryptophan synthesis (EC 2.6.1.85)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.6.1.85

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (776 amino acids)

>mRNA_5301 K13950 pabAB para-aminobenzoate synthetase (Rhodosporidium toruloides IFO0880)
MASDTGRRRLPTVLVLDFWDSYTLNVLRLVHQIAAGIHFDGEQEWDCTDWQDRVVVLNVD
SLSWDSFEHDILPHIDCVVLGPGPGTPHRQADFSWPTRLIQQVGDRVPVFGLCLGLQGLA
TSFGGTVVEAFSPKHGQISLIRHTAGLNDSRSLFTDVPSEFEVVQYNSLVVDPKSLPAEL
EAIAWTEDASGADEIMALRHRERPLYGVQFHPESISSTCGARILSNFFHLALDFHASASP
SRHSSSNLPRHILSLSTACRPPPPRPSSSNPNLRYESRTEKIESDRDWRPQRVFEELVKG
RSPLGEVWLDSARPTALPQYAHLFAPQATFAYSVASHSLLIRDAAASRQVHLPAAATFFT
TISDAQQALQHATHDSRPDGCPPCPVGFVGSIGYEMKDVTLPLSARPRSRLYEDDKPEAV
LAFADRVLSYSYDSGEWFASGLVVTAQRPEEADDPTSGLGAERKEWDGWLSTIRQTLAST
PPRTPSQTPAPLPTDFAPDQSRSSYMESIELARQSIIAGNAYELCLTTQFRSTLPADSPL
VADPYPLYLQLRATNPAPYSAYFYLLSSDFTLLSSSPERFIRIDRDGRADMKPIKGTVRR
ALDDFVEDERRKQALEADTKERAENLMIVDLIRNDLLASCTVESVEVPKLMKVETYQTVH
QLVTTVVGQLGKGVAPFEAMARAFPPGSMTGAPKLRSLQLLDELERQVPRGAYSGVFGYL
AVDGSSDWSVVIRTLVKRGRELTLGAGGAITHLSDPAKEWEEVLTKVDAVLGRKAS