Protein Info for mRNA_5356 in Rhodosporidium toruloides IFO0880

Name: 13724
Annotation: K07748 E1.1.1.170, NSDHL, ERG26 sterol-4alpha-carboxylate 3-dehydrogenase (decarboxylating)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 757 transmembrane" amino acids 28 to 47 (20 residues), see Phobius details amino acids 489 to 509 (21 residues), see Phobius details PF04321: RmlD_sub_bind" amino acids 30 to 189 (160 residues), 29.5 bits, see alignment E=1.5e-10 PF01073: 3Beta_HSD" amino acids 30 to 253 (224 residues), 153.8 bits, see alignment E=1.7e-48 PF16363: GDP_Man_Dehyd" amino acids 31 to 246 (216 residues), 38.7 bits, see alignment E=2.9e-13 PF01370: Epimerase" amino acids 31 to 252 (222 residues), 100.2 bits, see alignment E=4.8e-32 PF13460: NAD_binding_10" amino acids 33 to 180 (148 residues), 41.8 bits, see alignment E=4.1e-14 PF02719: Polysacc_synt_2" amino acids 75 to 144 (70 residues), 27.5 bits, see alignment E=6.3e-10 PF07993: NAD_binding_4" amino acids 94 to 238 (145 residues), 31.9 bits, see alignment E=2.8e-11

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (757 amino acids)

>mRNA_5356 K07748 E1.1.1.170, NSDHL, ERG26 sterol-4alpha-carboxylate 3-dehydrogenase (decarboxylating) (Rhodosporidium toruloides IFO0880)
MRQADPAISASAGRPFTMSTSPSPSRESYAVIGGEGFLGAALVSALLERHPASRVASLGL
TQRRFDPEGEYRFFRTDITSRESIVEAFRASGATTVFHTASPHANATPEMWQKVNVQGTE
AVVQACKEAGVRKLVFTSSMTAVYQPGVPLTNVDERLPRIETEEKLPTYAGTKAAAEKIV
LDANGKDGVLTCAIRLGGIIGPGDRQVLPGFIGVWKDGQSAFQMGDNRNMLDFVTVKNAV
HAHLLAADKLDAPPLSPDQFEVRMKPVACTVPRRNLPTSEQPDASAAKPDPPLPASRNRW
NQFFSLTDDPSSAPSLSVAGQAFFITNGEPVPFWSFARAVYFAYSRRPPRWFEPVVLPSG
VGMLYATLCEWAGWCVGKRPEQCAVNRAYMQYVLHDLYMDIERARRLLGYEPVESLEEGI
RSGVEWYKADEERQQRRKEAETIPLTCFRPASLLSRLAPALLARNACGISAPPPDPSSRG
LPRARRRRFFCSIARPHMAAFLVLAALRAGETLSDLRSPLIPPPIDHPAVFASQHRSAST
TPSPASSRPSTASSASSTLSSSHPPLTERSLRASHLAWLVRVRDLSARHLALVDARSKNW
TSCWAGKVSSRHIRAVKKAIEEAQWVEERLRLAIGWCKEKGLRKVSVKRLLGGKGLAYRP
THTSFPPSLLDLPYPLPLAFDANFLILTVPRPPPISRHRRAEEDEVEALPVYREEADHEL
GERMLERGLEDVVIGGVGVEQYERETHGQAAPVAVVA