Protein Info for mRNA_5402 in Rhodosporidium toruloides IFO0880

Name: 13770
Annotation: KOG2938 Predicted inosine-uridine preferring nucleoside hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 448 transmembrane" amino acids 23 to 40 (18 residues), see Phobius details PF01156: IU_nuc_hydro" amino acids 9 to 371 (363 residues), 165.4 bits, see alignment E=1.2e-52

Best Hits

Predicted SEED Role

"Inosine-uridine preferring nucleoside hydrolase (EC 3.2.2.1)" in subsystem Purine conversions or Queuosine-Archaeosine Biosynthesis (EC 3.2.2.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.2.2.1

Use Curated BLAST to search for 3.2.2.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (448 amino acids)

>mRNA_5402 KOG2938 Predicted inosine-uridine preferring nucleoside hydrolase (Rhodosporidium toruloides IFO0880)
MTHDEAPVPCIIDTDPGVDDVLALLLALSSPHLLILSITLTHGNCTLSSASSNLQKLFYA
LERQLEADQTGRERERYCNVDPAWRKKWGAGPIEVYLGSEGPIEGEAVTAKYFHGQDGLG
DAATRHPDLTPPSSHTSSLFTLHSSTPALEGVSSLLSRHPANSIAYVALGPLTSLAQLHR
ATVREGKMRESALSKFGVILSMGGAVEHPGNTSPVAEFNYYADPFAAQTIFSLALPNLYI
LPLDLTSYLTLPFSLYASRVDRSFSSTLSPSNPASKSALTHFTTSFLERTVEIMRSFGGD
AMELHDPTVVYCLIDWARNGRRRNGASGRGFGVDGEEGEVAPGWAWRHYDFEVETIGAIT
RGMLVRDLRASSRSTTSLTSRTGLTLRTAAIDALDIEEVEAHRAEGEGSREEADLRRRRS
GARVVMGSPGSEKLRGELVRSVWGVELE