Protein Info for mRNA_5588 in Rhodosporidium toruloides IFO0880

Name: 13956
Annotation: K04646 CLTC clathrin heavy chain

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1200 1300 1400 1500 1600 1662 PF01394: Clathrin_propel" amino acids 156 to 200 (45 residues), 28.8 bits, see alignment (E = 2.6e-10) amino acids 269 to 300 (32 residues), 23.9 bits, see alignment (E = 9.6e-09) PF09268: Clathrin-link" amino acids 346 to 366 (21 residues), 37.9 bits, see alignment (E = 2.2e-13) PF13838: Clathrin_H_link" amino acids 368 to 433 (66 residues), 103.9 bits, see alignment (E = 8.4e-34) PF00637: Clathrin" amino acids 553 to 691 (139 residues), 97.7 bits, see alignment E=1.5e-31 amino acids 701 to 839 (139 residues), 73.9 bits, see alignment E=3.1e-24 amino acids 847 to 981 (135 residues), 101.5 bits, see alignment E=9.9e-33 amino acids 993 to 1133 (141 residues), 106.7 bits, see alignment E=2.4e-34 amino acids 1142 to 1280 (139 residues), 100.2 bits, see alignment E=2.5e-32 amino acids 1287 to 1430 (144 residues), 109.9 bits, see alignment E=2.5e-35 amino acids 1438 to 1578 (141 residues), 100.5 bits, see alignment E=2e-32

Best Hits

Swiss-Prot: 60% identical to CLH1_MOUSE: Clathrin heavy chain 1 (Cltc) from Mus musculus

KEGG orthology group: K04646, clathrin heavy chain (inferred from 65% identity to aor:AOR_1_1392144)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1662 amino acids)

>mRNA_5588 K04646 CLTC clathrin heavy chain (Rhodosporidium toruloides IFO0880)
MVDRPIAFQELLQLTALGIQPGSIGFATLTLESDRFVCVREEVNGAKQVVIIDMLDPNNV
VRRPISAESAIMHLDDKVIALRAQRQLQIFNIEQKAKVRAHLMHEDVTFWKWISPTTIGI
VTETAVYHWTCYAPSSQPDAQTSDTPVKVFDRHASLAGNQIINYRVTPDEKWLVLVGISS
NTTNPAGFKVKGAMQLYSKERGVSQPIEGHAASFAEIRLEGASDDTKLFTFAVRTATGAK
LHVVEIDHQANLPAYAKKAVDVFFPPEATNDFPVAMQVSKRYGIVYLVTKYGFIHLYDLE
SGACIYMNRISGETMFTTCEHRATSGIIGINRKGQVLSVTVDEEVMIPYILSTLNNTELA
IRIASRGGLPGADDLFQRQFAQLFQSGDYSGAAKVAAGSPRGILRTSQTIDMFKGVPVQQ
GQLSPILQYFGILLERGKLNKYESLELARPVLVQGRKQLLEKWLKEDKIECSEELGDIVR
THDMTLALSVYLRANVPNKVVACFAETGQFAKIIVYAKRVGYTPDYAALLQHVTRLNPEN
GAEFATQLVNDEMGPLVDIERVVDIFMSQNMIQQATSFLLDALKENKPEQGHLQTRLLEM
NLLNAPQVADAILGNNMFSHYDRPRIANLCEKAGLLQRALEHYEDINDIKRVVVHTNLIP
AEYLVEFFGKLTVEQTLECFNEMLKVNIRQNLQVVVQAATKYSDLIGPVRLIELFEKFKT
AEGLYYYLGSIVNLSEDSEVHFKYIQAATRTGQIREVERIVRESNFYNPEKVKNFLKEAK
LPDQLPLIIVCDRFDFVHDLVLYLYQNGMTNFIEVYVQRVNSARTPQVIGGLLDVDCDEN
TIKALLASVTGPVPVDELVDEVEKRNRLKLILPYLEAKIAAGQQDPALYNALAKIKIDSN
NDPESFLKENSIYDPLVVGKYCEKRDPYLAYIAYAKGLCDDELISITNDNQMYKHQARYL
VKRRRLELWQQVLQGDNLHKRQLIDQVVAAAVPESTDPEDVSVTVKAFLSADLPSELIEL
LEKIVLDQSAFSDNANLKKLLMLTAIRADKGRVMGYIDKVEGFDVQEIASIMIEHGLYEE
AFTLYRKNGMHLEATNVLVEYIVSIDRAQQYADKVDQPAVWSRLGKAQLDGLRIKDAIDS
YIRAEDPSNYLEVIETASRAGKSEDLVRYLQMARKTLREPAIDTELAVSYAKTDRLRDME
DFLGMTNVADLLSAGEKAFDAGLYEAAKLLFTSISNWARLATTLIYLGENQAAVDAARKA
GNTQVWKQVNAACIEKKEFRLAQICGLNLIVHAEELQALVRLYEYRGYVDELMALLEAGL
GLERAHMGMFTELSVLYAKYKPERLMEHLKLFWSRINIPKVLRAAEQAHLWPELVFLYVH
YDEFDNAALAMMERSADAWEHNQFKEVVVKVANIEIYYKALNFYLEQQPMLLNDLLSVLA
PRIDHTRVVKMFQKADELPMIKNYLISVQKNNIPAVNEAFNDLLIEEEDYKTLRDSIDTN
DAFDAMGLAARLEKHDLLEFRRLASHLYGKAAKWDRSISLSKEDKLFKDAITTAAVSNST
DVAEELLRYFSDIGSRECFVALLFAAFDLIRPDVAEELSWRHSFHDTYMPYRLQVERSRA
DQVASLAKKLEELSSKTVAKEEEENSQPMLGLMPQTLALGYY