Protein Info for mRNA_5743 in Rhodosporidium toruloides IFO0880

Name: 14111
Annotation: K05672 ABCC12 ATP-binding cassette, subfamily C (CFTR/MRP), member 12

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1200 1300 1400 1480 transmembrane" amino acids 182 to 203 (22 residues), see Phobius details amino acids 240 to 261 (22 residues), see Phobius details amino acids 273 to 287 (15 residues), see Phobius details amino acids 330 to 357 (28 residues), see Phobius details amino acids 424 to 449 (26 residues), see Phobius details amino acids 458 to 478 (21 residues), see Phobius details amino acids 889 to 913 (25 residues), see Phobius details amino acids 930 to 954 (25 residues), see Phobius details amino acids 1003 to 1021 (19 residues), see Phobius details amino acids 1027 to 1045 (19 residues), see Phobius details amino acids 1111 to 1132 (22 residues), see Phobius details amino acids 1143 to 1160 (18 residues), see Phobius details PF00664: ABC_membrane" amino acids 197 to 474 (278 residues), 94.1 bits, see alignment E=2.5e-30 amino acids 893 to 1155 (263 residues), 146.1 bits, see alignment E=3.5e-46 PF00005: ABC_tran" amino acids 617 to 751 (135 residues), 72.4 bits, see alignment E=1.1e-23 amino acids 1223 to 1392 (170 residues), 99.1 bits, see alignment E=6.2e-32

Best Hits

Predicted SEED Role

"ATP-energized glutathione S-conjugate pump, putative"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1480 amino acids)

>mRNA_5743 K05672 ABCC12 ATP-binding cassette, subfamily C (CFTR/MRP), member 12 (Rhodosporidium toruloides IFO0880)
MPSPTSSVTRAESHERDYDKAEKGGSAASASDKEGQQEDVDKGLPMAASNDIKGTDIAHI
KRRWWLPKPREPYKSFEDAEEIPFATANFFSKITFYWIQPMLITGYQRTLVPTDLWKLHE
DFQASFLADKLVANFERRRKAVEAWNKALEDGSYKPSALRRAWWRVGKAFGGKGDGKRQV
GLALAISDTFFWRFWSAGILKVISDGLLVTSPLVTRALITFGTKAYAAHRGIPGYEPDPI
GVGIGLAFGLWGMQIVASLCLHSFFERSAGTGVLVRASLIAAIYRKAMVLSGKARTVITN
GRLVNHIGTDISRIDFCAGFFHMSWTAPIQLLVIMAILLVQIGPSCLVGIAFLLLMIPPQ
SWAMKKMFGFRRKAMVWTDKRARLIGELLGGMRILKFFAWEIPYLAKLQEYRAKELRQVR
NLLVSRAATTGVAMSLPTLATVLAFITYASTGHQQTAQSIFTSFTLFQLIRMPLMMLPMS
LSTITDAKNALGRLVEVFLADEREVTLDVNPSAKFAVEVTDADFQWESPPPDSAPKSKKE
QAKLAAKVKKEAKSAKKERKEKEKKAKVELKVAENAPADPESTENSGDATAGVPDATGVK
GQEDPTTTPEEKEVLQLRGVNLKIPRGQLCAIVGAVGSGKSSLLQALVGEMRKTRGDIKF
GGTIAYAAQQAWMQSCSLKDNILFGQPYDEERYRRVIHDACLEADLEMLPYGDATEIGEK
GVTLSGGQKQRVNIARTLYYPADIVLLDDPLSAVDAHVGKALFDNAICGSLAGKTRILVT
HALHFLPRVDYIICLDHGKITQEGTYAELVADKEGAFSQLMEEFGGDVEEKSEEKDEKEE
EAVEEAGKDGEKKDEQPKAKALMQEEERATGSVSGAVYARIFRLAKGWYTFPLLFFAIAL
QQGAQVLGSYLLVWWQEDSFNQSMGFYEGLYAMFGILQAIFSFVMGVATTIIGYNTSRSL
HHAAINGVMHAPMSFFDTTPLGRIMNRFSKDIDTVDNTLSDSFRMFVSTASSVIGAIVLI
AIVQQWFLLVVACILCLYAFAARFYRQSARELKRLDNLLRSSLYAHFSETLSGMATVRAY
GEQEKFLKQNEAYIDLENRAYMLTVINQRWLGLRLDFFGSCLTFAVAMFSVGTRTSISPS
QTGLVLSYILTISQAFSWMVRQGAEVENDMNSVERLLHYANNLEREAPAEIPETRAPAEW
PSGGAIEFKNVVMRYRPDLPPVLKGLNLSVRPGEKIGVVGRTGAGKSSIMQTLFRIVEVS
SGAIEVDGIDISKLGLADLRKKIAIIPQDALLFAGTVRTNLDPFAEHEDAELYDALKRAW
LVDRDQPPPRASMGDKSSEPSSASTPTASRFTLDLAIEDEGQNLSVGERSLVSLARALVK
DSKIIVLDEATASVDFATDSRIQATIRSEFKDKTLLVIAHRLRTIIDSDRVLVMDAGAVA
EYDTPINLFRAGGIFHGMCERSGITERDILETEFALPTQQ