Protein Info for mRNA_5810 in Rhodosporidium toruloides IFO0880

Name: 14178
Annotation: K02730 PSMA6 20S proteasome subunit alpha 1

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 249 PF10584: Proteasome_A_N" amino acids 6 to 28 (23 residues), 53.3 bits, see alignment (E = 1.6e-18) PF00227: Proteasome" amino acids 32 to 217 (186 residues), 169 bits, see alignment E=8.5e-54

Best Hits

Swiss-Prot: 63% identical to PSA6_MOUSE: Proteasome subunit alpha type-6 (Psma6) from Mus musculus

KEGG orthology group: K02730, 20S proteasome subunit alpha 1 [EC: 3.4.25.1] (inferred from 60% identity to aor:AOR_1_1196154)

Predicted SEED Role

"proteasome subunit alpha1 (EC 3.4.25.1)" in subsystem Proteasome eukaryotic (EC 3.4.25.1)

Isozymes

Compare fitness of predicted isozymes for: 3.4.25.1

Use Curated BLAST to search for 3.4.25.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (249 amino acids)

>mRNA_5810 K02730 PSMA6 20S proteasome subunit alpha 1 (Rhodosporidium toruloides IFO0880)
MSRSSYDRTLTIFSPEGRLYQVEYAFKAITTSGHTSLAIRGAGVSVVITQKKVPDKLLDP
ESITHIFNITPSIGCVMTGRTADARSQVQRAQSEASQFRYKYGYEITPDLLAKRIANINQ
VYTQRAAMRPLGISMIIVGFDPQYGPQIFKLDPAGYYVGFHATAAGQKQQEATNVLEKGF
KKGWKFESKDEVVELALSTLSQVLSTDLKAGEVEIGVAEESKVEGRGQFRKVRRRFFSTD
LRRRSHTSC