Protein Info for mRNA_6001 in Rhodosporidium toruloides IFO0880

Name: 14369
Annotation: KOG1575 Voltage-gated shaker-like K+ channel, subunit beta/KCNAB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 332 PF00248: Aldo_ket_red" amino acids 17 to 311 (295 residues), 243.4 bits, see alignment E=1.5e-76

Best Hits

Swiss-Prot: 47% identical to YAKC_SCHPO: Aldo-keto reductase yakc [NADP(+)] (yakc) from Schizosaccharomyces pombe (strain 972 / ATCC 24843)

KEGG orthology group: None (inferred from 47% identity to spo:SPAC1F7.12)

MetaCyc: 38% identical to perakine reductase (Rauvolfia serpentina)
RXN-12673 [EC: 1.1.1.317]

Predicted SEED Role

"Aldo-keto reductase"

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.1.1.317

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (332 amino acids)

>mRNA_6001 KOG1575 Voltage-gated shaker-like K+ channel, subunit beta/KCNAB (Rhodosporidium toruloides IFO0880)
MTKTVQIDAHTTVPVPGFGAMGMSAFYGQINDDESKATLRKAIEIGCTCWDTSSMYGWGH
NEKIIGEVLKEGDNRKKVFLISKFGLKQDGKGGMVVDGSPQNVIDALEQSIKDLGGLYPD
AYLLHRVDKNVPIEETVRALDALRKEGKTKYIGLSECSAATLRRASKEAQIDFVEVEYSP
FELVMERNGVLEACRELGVKVLAYSPLGRGFLTGRYKKPEDFSLASGDYRAAFPRYTKEN
FDRNYKIVEELERLASKKGCKSGQLALAWLMAQGDIIIPIPGTKSEKYLLENFAAREINL
SAEEVAEIRKVCEENAPVGDRYPESAMHTLDG