Protein Info for mRNA_6050 in Rhodosporidium toruloides IFO0880

Name: 14418
Annotation: K03942 NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR01959: NADH oxidoreductase (quinone), F subunit
  • amino acids 56 to 468 (413 residues), 619.1 bits, E=1.2e-190
• PF01512: Complex1_51K
  • amino acids 95 to 268 (174 residues), 158.8 bits, E=1.4e-50
• PF10531: SLBB
  • amino acids 294 to 344 (51 residues), 31.3 bits, 2.4e-11
• PF10589: NADH_4Fe-4S
  • amino acids 384 to 466 (83 residues), 108.1 bits, E=2.8e-35

Best Hits

Swiss-Prot: 73% identical to NDUV1_NEUCR: NADH-ubiquinone oxidoreductase 51 kDa subunit, mitochondrial (nuo-51) from Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)

KEGG orthology group: K03942, NADH dehydrogenase (ubiquinone) flavoprotein 1 [EC: 1.6.5.3 1.6.99.3] (inferred from 81% identity to cci:CC1G_03104)

MetaCyc: 75% identical to NADH-ubiquinone oxidoreductase 51 kDa subunit (Arabidopsis thaliana col)
NADH-DEHYDROG-A-RXN [EC: 7.1.1.2]

Predicted SEED Role

No annotation

MetaCyc Pathways

• aerobic respiration I (cytochrome c) (3/4 steps found)
• aerobic respiration III (alternative oxidase pathway) (2/3 steps found)
• NADH to cytochrome bd oxidase electron transfer I (1/2 steps found)
• NADH to cytochrome bo oxidase electron transfer I (1/2 steps found)
• Fe(II) oxidation (2/6 steps found)
• NAD(P)/NADPH interconversion (2/6 steps found)

KEGG Metabolic Maps

• Oxidative phosphorylation

Isozymes

Compare fitness of predicted isozymes for: 1.6.5.3, 1.6.99.3

Use Curated BLAST to search for 1.6.5.3 or 1.6.99.3 or 7.1.1.2

Protein Sequence (517 amino acids)

>mRNA_6050 K03942 NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1 (Rhodosporidium toruloides IFO0880)
MQLARPIFAAATRVGGRRFATPAAVQHTARRAYAAVQDAAANPVKRHGGLRDQDRIFTNA
YRQGDHGLKGARARGDWHRTKDIVLKGDSWIIQQIKDSGLRGRGGAGFPSGLKWSFMNKP
GWEKDGRPRYLVVNADEGEPGTCKDREILRGDPHKLIEGCLVAGRAMNANAAYIYIRGEF
YMESDHVEQAIQEAYKAGLIGKNACGSGYDFDVYLHRGAGAYICGEETALIESIEGKQGK
PRLKPPFPADTGLFGCPTTVANVETVAVAPTIIRRGASWFNSFGRERNSGTKLFCISGHV
NTPCVVEEEMSIPLQELIEKHCGGVRGGWDNLLGIVPGGSSVPILPKNHCEEALMDFDSL
RDLQSGLGTGAVIVMNKETDVIRAIARFAKFYKHESCGQCTPCREGTTWLEKMMDRMVVG
RAHEREIEMLWELTKQIEGHTICALGDAAAWPVQGLLRHFRPEVEKRIHDFKQREGQVLF
GGHLLKDQNPDIALPDNIGISLPGVAPGAGNSPNVSP