Protein Info for mRNA_6068 in Rhodosporidium toruloides IFO0880

Name: 14436
Annotation: K01855 PUS3, DEG1 tRNA pseudouridine38/39 synthase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 670 PF01416: PseudoU_synth_1" amino acids 320 to 425 (106 residues), 76.8 bits, see alignment E=8.7e-26

Best Hits

Predicted SEED Role

"tRNA pseudouridine synthase A (EC 4.2.1.70)" in subsystem tRNA processing (EC 4.2.1.70)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 4.2.1.70

Use Curated BLAST to search for 4.2.1.70

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (670 amino acids)

>mRNA_6068 K01855 PUS3, DEG1 tRNA pseudouridine38/39 synthase (Rhodosporidium toruloides IFO0880)
MPLPHNPERALLVQQIQNLQHRLAKLDNEDPPSSPSETPTPAPGLASTSKANSPKPPVPL
TGKRARKAQAATGPLPPSLANAPKRHIALLFSYEGWAHSGLAYQPKGVYTPLPTVEGCIL
DALEKARLIEPITESEGFGCGFERCGRTDAGVSSSAQVINLWVRSDLEDPMKLNGREIDP
DSPEGRRFARSGSPSRPRSSSSASSSSSDSVYGSGKRKAPSDVEIPYVTLLNKHLPPSIR
MHAWSPISATFSSRYSCIWRHYKYFFSTSPISPLLASRFDFGAAYEAAGALPEHAAEWQE
RLRRVDWNGLQLDVDLMRDAVKRLVGEHDFRNLCKIDPPKQLKLHIRTVNSASIDPLEGE
GGDMFVLNLRGGAFLYNQVRHIVAILFLVGARLEHPSLVDKLLWTSDRTSHTVSQNAPPA
GQPDHDILDQKPSYQMAEDLPLILWQCGFNSTEFDWRTDNAPRPGDVNESTTSYLDHNGR
EKQPVDQADNFRKLFLEMNETYTEYRLKAIVLKHHLASFAFHAPPIAPPSRPASPTPESS
CDAPPSRLRPASPPRRPLSVRAEQTLFTPVGAGKVARTTSYTPVLERKRGETPDVINARW
AQGRGAQKMQRRKDNQEAADKTREVHLKIKAEAMELAKRLEEERLQALRLVDSVSSEPVS
GVATPDKGES