Protein Info for mRNA_6162 in Rhodosporidium toruloides IFO0880

Name: 14530
Annotation: K11427 DOT1L, DOT1 histone-lysine N-methyltransferase, H3 lysine-79 specific

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 732 PF08123: DOT1" amino acids 483 to 686 (204 residues), 193.1 bits, see alignment E=2.2e-61

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (732 amino acids)

>mRNA_6162 K11427 DOT1L, DOT1 histone-lysine N-methyltransferase, H3 lysine-79 specific (Rhodosporidium toruloides IFO0880)
MFTNSRPLPKSATSSSTPSRPVPTITVKPKISVVPPPSSPLSSIASSSASSPANASNGSS
TASNKPRIQLTTKKVTVVKSVAQPPPASTAPGQPRSINKYPAPAPKPKEVKEKAKKKKGM
LRGLSSDEDEVESEEERPRKKVKKGSSSSSASSASGKGRLKVNGTNGSRAASPLRQQHSS
TSNGTLRSSSPLSSLPSTSSDEEETESELSSVDEDYFARTLKREDGGAIAVRDPSAKALP
EGAIAELGRSGEWLVVNNRGAYRDYFVDLTDPGRPVTEWAGSEIPTVELELPGDGAKERF
ALLAPKSDDEYNPIEDVMSTVLAVLDHFLTPEQASHYFGHSPGKTSFGAFLYNRSTSNSR
SGTPSAFSVPEKLATRPSSTTSLAPSPAPSAAADSPLPFTLDFALLATSTPPPASTPEID
RTPLIRQLEKARAKRDGPSFLAALARYNSTLSTLKSTGLIRANIAAMKGLKEKVWTKVFQ
QCYDRAVGPGIEDLRKYEAFSDNVYGELLPKFMNQIFDKTHLGPNSVFVDLGSGVGNCVV
QAALATGATSYGFENMPHASSLARDQLAEAEKRFRMWGLGGGPMKVVEADFCEYPEVMQV
LRTASVVLVNNEVFTSTLNQRLSWLFLELPDTCKIVSLKPFLPPNFSLSAHNANSPLAII
NQGPALHYGPGSVSWKEGGGSFFVSRVDRARVQRWLEREGKREREKERKRAERGSSRGSS
VAMSRNGSAAGK