Protein Info for mRNA_6180 in Rhodosporidium toruloides IFO0880

Name: 14548
Annotation: KOG0218 Mismatch repair MSH3

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1025 PF01624: MutS_I" amino acids 155 to 265 (111 residues), 85.5 bits, see alignment E=6.4e-28 PF05188: MutS_II" amino acids 274 to 331 (58 residues), 24.7 bits, see alignment 5e-09 PF05192: MutS_III" amino acids 414 to 761 (348 residues), 111.1 bits, see alignment E=1.6e-35 PF00488: MutS_V" amino acids 823 to 1016 (194 residues), 224.9 bits, see alignment E=1.8e-70

Best Hits

Predicted SEED Role

"DNA mismatch repair protein MutS" in subsystem DNA repair, bacterial MutL-MutS system

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1025 amino acids)

>mRNA_6180 KOG0218 Mismatch repair MSH3 (Rhodosporidium toruloides IFO0880)
MLHRARSFSSPLVRLASPRTTSLGRLASVRHASTAGKEDDEGAGRPRGKVLLDEHGIERR
ALPPLGFDGKPIKLSLSSNWTEPEEAAKLKAKKPRKATTPLKKEAKKADEGQEGIEAEIG
AEDAPAKKGRKKQSAQEDAEEGVEEMSYRQRRLTDLEKQIKGFTEQYPDALVLTQVGSFY
EAYWEQAKLVTKLLGMRLTSKSFGNAKAPMAGFPLTQMTKHASTLVQQGHKVVIVDEYQD
LLRQKKGLIERRVSRVITPGTGVDEAFVKIESPNFVLALGVVDGSSEGETIGMAYRDVST
GASFTRTSTLATLRDNILLVQPKEIVVDEQLGGTVLGKQISELLEGERMREGTMISTTST
DAIPSSSRKAPSVTQTAESVLLAYLARTLVSNPPPRTKSTYVDPASVMQMDAVTLQSLEI
RESLRGGLRGSLFGTVKRTVTPGGTRLLADRLCNPSTDLPTIYQRQALAQAGLGGLSVAR
PYIRGVLRSLDDTPRLLQRLAMNRASAANDLCGLKRTMRALDTIKLEISRALPKSAADAE
ANGWTVAQIRAIRELVEKLGQYPVLAGEIEAAIDEEALTKLEDAQELKAAELAELGETLV
AKAEEKRKKALKRGQLWGNEEAWYVRSAYSAKLQDLHDKLQRLRLAATDLQCDLQERYHA
PQLFLRDYKNTPTVRADMKDGWTKLDEDKRLAIFSRTGKTRDYIVSDWSTLYKEIESTQS
KIRRLETDATQVLIARVLEHFDDLTATGDALAELDVALGFAEVAEELDWVKPEVDDSRTL
EIVNGRHPTVEAALAAQNRAFHANSLTMRHPDDAAEQPSFIHVLTGPNMAGKSTFLRQTA
LIAILAQSGSYVPAESARIGVFDRIFSRVGARDELDRDRSTFMIEMDEATSILEMATARS
LVLLDELGRGTSPIDGLAIAYAALEHLTHVNRSRTLFATHYHRLGQLLGYEEENPRGKGP
WEGVEFWCTDLEESEESVRYLHAIRRGLNSDSAGLVVARLAGMPARAILEARRIRDMLLV
DGQVY