Protein Info for mRNA_6208 in Rhodosporidium toruloides IFO0880

Name: 14576
Annotation: K00006 GPD1 glycerol-3-phosphate dehydrogenase (NAD+)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 419 PF01210: NAD_Gly3P_dh_N" amino acids 77 to 247 (171 residues), 145.8 bits, see alignment E=1.7e-46 TIGR03376: glycerol-3-phosphate dehydrogenase (NAD(+))" amino acids 77 to 416 (340 residues), 422.3 bits, see alignment E=7.3e-131 PF07479: NAD_Gly3P_dh_C" amino acids 270 to 416 (147 residues), 145.4 bits, see alignment E=2.2e-46

Best Hits

KEGG orthology group: K00006, glycerol-3-phosphate dehydrogenase (NAD+) [EC: 1.1.1.8] (inferred from 68% identity to scm:SCHCODRAFT_54510)

Predicted SEED Role

"Glycerol-3-phosphate dehydrogenase [NAD(P)+] (EC 1.1.1.94)" in subsystem Glycerol and Glycerol-3-phosphate Uptake and Utilization or Glycerolipid and Glycerophospholipid Metabolism in Bacteria (EC 1.1.1.94)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.1.1.8, 1.1.1.94

Use Curated BLAST to search for 1.1.1.8 or 1.1.1.94

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (419 amino acids)

>mRNA_6208 K00006 GPD1 glycerol-3-phosphate dehydrogenase (NAD+) (Rhodosporidium toruloides IFO0880)
MSQNKQRKEGGQDGSDDETDKEGDDGEKERRPSLGESLSRKGSLKAPLPRRGSSPALAPF
LAKYDEFTGSPSGKLEKICVIGSGSWGTALARLAAQNAAEKDGFDEEVRFWVRQREIPGK
GLLTDIINETHENARYLPEMKLPENLVAVPSLTECVKGATLIVFCVPHQFLPPVIKELSQ
PGVLEKGARAISAIKGIDVDVKTAEIYTYPSIIEKKLRLPCSALGGANIALEVANEEFCE
TTIGCPGPEDCALWEAVFSTAMFRVHAVEDVAGVSLSGALKNVVALAAGFVDGLKMGGNT
KAAIIRIGLLEMSAFTLEFFPSASAHTFSHHSAGVADLITTSFGGRNRKCAEAFVTSGKT
FDELEKELLNGQKLQGVATAEEIYAFLKARERLDGYPLFTKVYQICKREISPEAIFEGI