Protein Info for mRNA_6249 in Rhodosporidium toruloides IFO0880

Name: 14617
Annotation: K01052 LIPA lysosomal acid lipase/cholesteryl ester hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 604 transmembrane" amino acids 191 to 215 (25 residues), see Phobius details amino acids 433 to 471 (39 residues), see Phobius details amino acids 525 to 540 (16 residues), see Phobius details PF04083: Abhydro_lipase" amino acids 249 to 305 (57 residues), 59 bits, see alignment 1.4e-20

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (604 amino acids)

>mRNA_6249 K01052 LIPA lysosomal acid lipase/cholesteryl ester hydrolase (Rhodosporidium toruloides IFO0880)
MGDNYKDYSRQPTHVDRSDHPSADHEYGGNTRGEPGEKNWADMTTKDLERAAQDNHDRPL
GTLVGDWRVKEKEGPEEGYVGGTSAFGAPPGSDLRDYAENERGDVGRAYGQPEDDAYYGG
SRGGRQSAFSQAYTAEDRYSYEPQGRQKQDFFSKNDDRGYDPDDTNFVNDVPPRPAYRTL
TFYERCWLAGFQLGSFLGTTLAFNMIVIMSLVVYVTNKLNPLHKSPPRAKVEKEFEERIT
GERFSTRAAYYANYWGYDCEDIDVETEDGFILRLHHLTSKKHEKRGHPVILQHGILSTSV
TFMVNEERSLAFWLLEQGYDVWLSNIRTNFKMPHRHYSRADPRYWAWTVKEIGLYDLPAI
VDYVGKETGLKPAYIGHSQGCGTMYLALSRGMRPDLGNKISCFISLAPAVYAGPCLRHFP
FSLMRKFAGSRKVWKLVFGVREFIPAIGILQAVLPGWLFGHFANPTFAFIFGFHDHNWVK
RQIPKFFRTVAVPNSSELLLYMNVFAGKNCVFDTRTTEPWFPASMPPLAIFYGTLDTLVL
GKPLVERIRSHEPNVRLVKAVALENYEHQDPIWAHTAIREVYPGIREVIEETRYGYKRGK
HDRV