Protein Info for mRNA_6313 in Rhodosporidium toruloides IFO0880

Name: 14681
Annotation: K10592 HUWE1, MULE, ARF-BP1 E3 ubiquitin-protein ligase HUWE1

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 500 1000 1500 2000 2500 3000 3500 3819 transmembrane" amino acids 460 to 482 (23 residues), see Phobius details amino acids 507 to 521 (15 residues), see Phobius details amino acids 1958 to 1975 (18 residues), see Phobius details amino acids 1987 to 2007 (21 residues), see Phobius details PF06012: DUF908" amino acids 90 to 435 (346 residues), 304.1 bits, see alignment E=4.5e-94 PF06025: DUF913" amino acids 502 to 861 (360 residues), 318.6 bits, see alignment E=1.4e-98 PF00627: UBA" amino acids 1347 to 1383 (37 residues), 42.6 bits, see alignment (E = 1.1e-14) PF14377: UBM" amino acids 2768 to 2800 (33 residues), 36.9 bits, see alignment (E = 4.5e-13) amino acids 2806 to 2839 (34 residues), 33.7 bits, see alignment (E = 4.5e-12) amino acids 2857 to 2887 (31 residues), 18.6 bits, see alignment (E = 2.5e-07) PF00632: HECT" amino acids 3515 to 3818 (304 residues), 303 bits, see alignment E=7.6e-94

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (3819 amino acids)

>mRNA_6313 K10592 HUWE1, MULE, ARF-BP1 E3 ubiquitin-protein ligase HUWE1 (Rhodosporidium toruloides IFO0880)
MARLKRQPKKGGSAHPGIASFINQLQQVPQHELPSLVQPLLEHGWEWPKTDLQHWVYPLN
RFDEILENVIRDYDLGSMEHCQTNEFTPRTKELLLSVLGFQKLLLENSTNRKIFNGFDRI
NDLLHTTDISVLLATLRLALRPAQQFSSINSSLNAAPFSEKRLLALAQSWGTREHGIELY
QLAEDKQLEVPLESQEPEWQFYRKAEPSKGASENKPQEQGMEVDPAELPATAPQASTSVS
TPAPVRRTASFAPYLHTPAREAPSTPAAPTTPAAGVSAQSWKSTEGLATIHLPNLRTTQK
SAIDILLDLAETHHVPDSDRLDLLQRIRIGQALSSQSAAARQQLLVVRLFALAVFAHSQS
EQAAQLKIFLYEPDLIAQVAELVHPERDAPVEIRSAALYALEAFGRRKSRTAEVASALNA
SVSHGVLMETVRKMAADLDTDEPETNVEYIDALFHVLTYMNIHTAIGSMVIGAGIVSVLL
DFLRNERRGYLQLLGANKANVLLDGFVSGYSNAFTAFMSAGGLNVWVARIKTEVDEAVSA
HADEAKELEASVKENALGFLPFQQGILLKSLLRALQRLLAGSGTTEGLRNVIDTSLLDSI
KTVMQNRRVFGPQIFSLAANIAATFVHNEPTSLAALQEAKVPDIFYDSLEGVIPAANEVL
QSIPHAIGAFCLNQAGLDQLLARPLIDKYFEIFTTREHVELLRDRDSAVILGSSIEELIR
HHPALKEKLMKGVHGVLEALKANGERFVVPDGEEGYNLVAASPVRDVPMQEAATASAGQA
TGAGQEQGSDQARQEQDAKDKDKKKDEEIMKNNEATDAIDVFGRFLEGLFQNSGQVIDDF
FGATDKVFETLLDLLVLPCSPAIMEKNNGYSSIAAMFRIATETKASEVLSCILRRTDKWM
KETEWFWNTTATDGLARESPLAAMVSPPADSLPDQQKRFRDITTLLSHISLFSDVFTNLT
YAYGKPATVILSVFTKPAEQGEVLERIGRVYRACQWENVAIRPTSFWTGEASQAATEELA
QNAPQGEAPTPAIAASRERQQEHAAEKAAVEAISTPATPDSPNIKLIQDVLQAFTRSTLP
LMQAILKLVLQRRTAEAAHRAVGQAVAEKLARFLRDSLEWPEAKELSTNLAYAAQSLILV
TKLLFDERPNGLQVQLLRSFVACGGFEAYLRLFERLQAVATEHFASTSDASSASPLIIPV
FGGLKTVLELLVRLTAVKTILEAQQTAILLTREKDPASRNYFNAPAFLVRLRATALPAIS
AMWEQPWLRKSPQNVVRSLVATLINVLKAEGEDQTDQPSRPEVGRPLGQVIADGNLAVGG
AANALNAMFGGGPLGALAGVPATPAAPDETRIAQLMDMGFPRGACETALRRTRNNVALAT
EYLLQHPDVVGAARDEEARQLLAPAPPAPPADAQPAQADNVEAAPPPLAPQDQPAEHVAP
AAEPQADVEMGDANAVGTAAEAAVSTTVAEEPPATPEPPIDDVKKELKVAREKIETGFIH
RTLELAEDFADLVFDVKNVFNSLAPASSAESGKPPFRPLLNELDSFTEESAVDAREAAIT
TRLRLIALITTDASYRETVESLRENVMSTVMRFERRYSAKSPAKDARPKWLAPLMLVADS
MLAIQDVPRPTEILSEGSDVPSVELVAQGPAWANERKALFELALDVLDKGVSTRDVFIST
LRLLLCLTRDHDAAAAFAQRDGVRTLLSSFAIDSPETKGCRSYAVMILRHIVEDQALLKS
VMEREIEGWFGSNRSKVADATGFIRATHSVALRNIATFLEAAKTTIKLVRADAPHHYHVT
LQRDEGTNAGKQIDSEPLKSPLNQEGGDSTDAAMGDAPTKAAGRATLSPAPQAVDAVVHL
LMQQALDTSKGALAPVPRLAEGAEPASNAATDALKKDAVDAHIPADTPLDDFYQSAFSLA
CLAELVASYNPCKASFLAFSTRKGGSKETVAPKSRSSFLYFLLNDLALSSSLAPLGDFDT
KRASSMWGWASLVIVGLCYDSAAASTLGNAADKESANEITIVRKAVLEVIARAFRDAMAS
SEPTESRYARLACLSDLCHRLLTARPFPNVNRPHSETSMQLAKLMLEKNFAVILTNALAD
VDLNYPHVNVLINAILRPLDHLTKIVTKLGRAKGALSGAAGAAKDDAMSSDLSSEDSSMM
SDGETVSDESDVELSPEDQAAADLYRNSALGMYEGELEQGQPEEFMSEDEEAYDEDDDEM
MEEEFDGSEFSDASDLDDDEDHGGRRFSDAEMEEMAAEDEDDLDGDSDGEGSIIDADDVE
EEILFEEGGDGEDQLEAFEAQFDAEEDDWVDEDDEEGGGPVDGGDELVFGGEAAMGEMDD
EEGVDEAGDSEGGFTDEEELLTGELEFDPEMTEQLRAQSTAQAYGWDPVTGGDGASARRN
RSLAEDMMMLGDAGADRPRTQNTAAPHPLLAESSSAEAAAEPAARRPRGQDGASRDSPAY
REWVRSVETMLGPGGVTTLEEILGTQGLSHLHGPDQVSVQLQPTAEGGMAVVIQPNPGAR
AAQHAHGHDAHRHAGTSATQPSSRSVARQLSDRINAASAFLPLQTNQRWYEESRILQGCV
LVNERIVRLANHLINVLHGPARESAKEERKKEEERRRKAEQEAKEVAERLEKEKRLQAEE
EERQRKKEEEEKAKEEADARGEAEASAGQASMEVDNEPTEEVPDDVAEVMNLARSLAAGL
AVPSTSGSTPAATSRQGTPAAALSTSAAAPSSGAPAPASEAAAPVASGSEDAPRPERITV
LVHGEEVDITDTGIDREFLEALPDDMRDEVIRQHLRETRARSTGPPPAVPEHINSEFLDA
LPPALRDEVLRQEAAAQRRAQAAPAPADQAADRADEPADFAEVNPADFLGTLDPALRSAV
LSAEQGNAPNPLDALLGGLLAAGSRARRGPAANAALQAVGGRAGGADRVGAALGQPGHAA
AKKSATHREVIQLLDKSGLATLVRLLFFPQPLKRHSLQRVLVNLCENGRTRVELVHLLLT
ILQDGTRDVSAVDKSFSQMSLRASRALVNKETPKRRAPETPGGSLPHFPGESVPNLIAQR
CLEALGFLVQANEQTSLYFLTEQEVPVSKRAAKKGKGKEKAAPTTTYPIIVLLGLLERPA
TLKTPAMMEAITTLLAQITRSLASIEKPTTAAPVAASQGPPATNVGTDEASSAAAVSTAP
PAEPANKDDDQKAKDAKDAPLTVEALSKNPPQIPAASLGHVVNVLDAGECSSRTFSQTLG
LIQNLSHLDGAREVILGELKARAEKISQEIVPSLVELLDTIGRDQPVGGVTLGKFTPASS
NQAKLLRILKTIDFFGAAPKRLPSTNSGEPASKSLSAEEEQVKQIYSSLSKSELWKRLGD
ALGGIEAKPDLLYLSTVLLPLIESLLVVNKFTDASSTEFIDFTTAHSKILNTMVRNNPSL
MSGSFAVLVRNSSMLDFENKRSFFFSRLHDRSQRKRPHYPTINLNVRRAHVFEDSFHVFN
RRSGEEIKYGKLNVKFYDEEGVDAGGVTREWFGVLARQMFNPGYALFQPQAADSLTYQPN
KSSAINENHLEYFRFVGRLIGKAIFDQRILEAHFSRSVYKHMLGKPVDHRDLESIDPEYY
KSLVWMLENDIEGIIDLTFSVERDEFGVMEVVDLIPNGRNIPVTNENKHDYVRRIADQRL
SIEIKDQMDALLKGLYDVVSKDLLQIFSERELELLISGLPTLDVDDMRAHTDLVGFSPSD
PVVAWFWRAVRSFSQEERAKLLQFVSGSSRVPLEGFAALQGMNGVTRFNIHKAGNNASLP
TAHTCFNQLDLPTGYESYEHFRRQLSLAIHEGATGFAFA