Protein Info for mRNA_6341 in Rhodosporidium toruloides IFO0880

Name: 14709
Annotation: K01867 WARS, trpS tryptophanyl-tRNA synthetase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 401 PF00579: tRNA-synt_1b" amino acids 58 to 147 (90 residues), 23.6 bits, see alignment E=1.5e-09 amino acids 215 to 346 (132 residues), 57.8 bits, see alignment E=6.1e-20 TIGR00233: tryptophan--tRNA ligase" amino acids 59 to 370 (312 residues), 314.4 bits, see alignment E=5e-98

Best Hits

Swiss-Prot: 67% identical to SYWC_SCHPO: Tryptophan--tRNA ligase, cytoplasmic (wrs1) from Schizosaccharomyces pombe (strain 972 / ATCC 24843)

KEGG orthology group: K01867, tryptophanyl-tRNA synthetase [EC: 6.1.1.2] (inferred from 74% identity to uma:UM03798.1)

Predicted SEED Role

"Tryptophanyl-tRNA synthetase (EC 6.1.1.2)" (EC 6.1.1.2)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 6.1.1.2

Use Curated BLAST to search for 6.1.1.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (401 amino acids)

>mRNA_6341 K01867 WARS, trpS tryptophanyl-tRNA synthetase (Rhodosporidium toruloides IFO0880)
MAIDYNHLIDQFGTRRIDDELLERFERLTGRKPHLLLRRGTFFSHRELNLILDRYEQKKP
FYLYTGRGPSSDSMHLGHMIPFIFTQWLQDVFDCPLVIQLTDDEKFLFKASLKLEQCHSF
AFQNAKDIIACGFKPEKTFIFSDLDYVGGAFYRNVVKISRLITARQSQQTFGFKLEDNVG
KWHFVAIQAAPSFSNSFPQIFGDKTDIPALIPCAIDQDPYFRLTRECAQRLKYKKPALIH
AKFIPSLLGAQSKMSASASESSIYMTDTQKEIKTKINKYAFSGGQTSIEEHRAKGGNPDV
DVSYQYLTFFLDDDAEVEQIAQDYRAGKLLTGELKQKTIALLQEFVKAFQERRAAVTDDL
VRQFMDPERKIDPTLRYGPGCTGEKPKAQATPVIKEPTSTA