Protein Info for mRNA_6518 in Rhodosporidium toruloides IFO0880

Name: 14886
Annotation: K05712 mhpA 3-(3-hydroxy-phenyl)propionate hydroxylase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 649 PF01494: FAD_binding_3" amino acids 6 to 409 (404 residues), 278.6 bits, see alignment E=8.8e-87 PF07976: Phe_hydrox_dim" amino acids 447 to 614 (168 residues), 157.3 bits, see alignment E=3.9e-50

Best Hits

KEGG orthology group: K03380, phenol 2-monooxygenase [EC: 1.14.13.7] (inferred from 48% identity to fgr:FG09110.1)

Predicted SEED Role

No annotation

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.14.13.7

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (649 amino acids)

>mRNA_6518 K05712 mhpA 3-(3-hydroxy-phenyl)propionate hydroxylase (Rhodosporidium toruloides IFO0880)
MVATNDCDVLIVGAGPAGLMLSTWLSKLKIRTRIVDKAPTKVLVGHADGVQCRTVEVFQS
FGFAQRLVDEGAHINEVVSWALDSKGDLQRTGRIPDNEPGTSRFPHAVLSQGRIERFLLD
AMKDFNDLTVQRSTAPVSMSVDQNLVGDFSPNSYPISVTVRRLTEEESVPTQLGAVPNGL
HRSNLLADDESDAAKGTKEAGAFDNAGEEETIRTKFLVGCDGARSWVRKHMGLSLEGDAA
GAVWGVLDAIVSETTFPDIRLKCTVQSKVGSILIVPRERDYVRFYIQIGSTKPGERFDRS
SVTPESIIETAKKIMAPYTLECSDFEWWTVYEVGQRLCKTFSHDKRVFIAGDACHTHSPK
AGQGMNTSMMDTYNLGWKLAHVLLGKATPDLLKTYSEERYKVAKELIDLDYKLSRMFSAK
PKEEGGDGDGVSLAEFKAFFKSLSRWASGTAVHYLPNMLVAPERQPALAPGLPTGMRFES
HLVVALADARPWHVGDRLVSDGRWRIILFAGDIREQEQKAKLEQVAAYLDTPDGPIRRYT
PPNDDLDSVIEILTIISNPRISVEPNAFPAILWPARKPYGSRAYDKLYADDSSPVTPNVR
GEIYKNLGIDPKTGCIAVVRPDQTVSLVCALDEHKQIGDFFAQFMVPRA