Protein Info for mRNA_6582 in Rhodosporidium toruloides IFO0880

Name: 14950
Annotation: K11517 HAO (S)-2-hydroxy-acid oxidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 493 PF00173: Cyt-b5" amino acids 5 to 75 (71 residues), 67.2 bits, see alignment E=1.7e-22 PF01070: FMN_dh" amino acids 117 to 470 (354 residues), 393.3 bits, see alignment E=1.4e-121

Best Hits

KEGG orthology group: None (inferred from 47% identity to nfi:NFIA_017510)

Predicted SEED Role

"L-lactate dehydrogenase (EC 1.1.2.3)" in subsystem L-rhamnose utilization or Lactate utilization or Respiratory dehydrogenases 1 (EC 1.1.2.3)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.1.2.3

Use Curated BLAST to search for 1.1.2.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (493 amino acids)

>mRNA_6582 K11517 HAO (S)-2-hydroxy-acid oxidase (Rhodosporidium toruloides IFO0880)
MLTGADVAKHNSSESLWMIINGKAYDLTEFQTNHPGGQKILLKFAGRDATEEYEPIHPPG
TIEEALPADKHLGEVDMSTLLPEQKIIEQAVPKPTTAGDAPMTLGACLNLDDIEKAAERL
LKPKAWAYYRSAADDERTHNWNRESFYSVRLRPRVLRDVTTVDLSASILGHTSSLPIYIS
PAAMGRLAHPDGEKCLARVAAAHQIPYMVSANASVGFEELASQAKEGQILFYQLYVNRDR
AKSEDILRRVAKAGYKAICVTVDAPVAGKRERDERAKLDDEAASDPNMQKAVKSTGPDAP
DAPQDEPSQGIAQALGSYVDPTLAWHDLEWVRKASGGLPIIVKGIQCAEDAALAAKNGAQ
AIILSNHGGRQLEGAPSSLETLLEIRKFEPWVLKKLEVWCDGGFRRGTDVLKAIALGARC
VGIGRPFMYSLVFGDEGVNKVATVLREELAQNARLMGATSMTEVVPSMVNARELEQNVYN
GPYESPVRALAKL