Protein Info for mRNA_6613 in Rhodosporidium toruloides IFO0880

Name: 14981
Annotation: K08740 MSH4 DNA mismatch repair protein MSH4

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 818 transmembrane" amino acids 508 to 528 (21 residues), see Phobius details amino acids 548 to 565 (18 residues), see Phobius details PF05192: MutS_III" amino acids 96 to 440 (345 residues), 111 bits, see alignment E=1.4e-35 PF05190: MutS_IV" amino acids 308 to 400 (93 residues), 29.1 bits, see alignment E=1.5e-10 PF00488: MutS_V" amino acids 492 to 685 (194 residues), 176.3 bits, see alignment E=1.1e-55

Best Hits

Predicted SEED Role

"DNA mismatch repair protein MutS" in subsystem DNA repair, bacterial MutL-MutS system

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (818 amino acids)

>mRNA_6613 K08740 MSH4 DNA mismatch repair protein MSH4 (Rhodosporidium toruloides IFO0880)
MLVKGLQSEFKDVPLIGVARKYWNEQTGFEFLTQLIVHDEDRLGVLTACKPKYYALSAIC
ALFNYLETSHSLSFAPKTLKIRYSALEGTCLIDADSVRNLELVSNMLNKNSKQHLLGMLD
KCCTAMGTRHLRSNILSPLTEPSVIDARLDTVEELVKSEERLRAIRKALEQLKSIDLDKI
VSRLLAAEKRPSTGTRSTSRGSIFPSFQSSTDPSSQIASKLDYLLSLRNFLSTLPTLRSS
VENSDSVILMQVEKVLQDDRLEQIRAVIEENVNPDIWKKGDDKRSGGRDSNGGRHARLFA
IKAEKKRLLDVARETWRENTSDVNDLCDTLREKYGLEGLTLMQGGKGSAYVFQLTKEEWD
EKRSEIGKAFTNVNILKKRVEFSSLDLQKRNARLQESEQEIYLMSEEILEEMFQEIRGCV
ACLYKCSEAIALLDMLAAFAELSSKEDYVRPEWTDTLAIKAGRHPLHEQFRMSDGSFVPN
DTYASDAASFQLINGPNMSGKSTLLRQIALLHVMAQIGCFVPTAYASFRPISALLTRLSN
DDNLESSLSTFASEMATMSMILAALQAHEGRRCLVIVDELGRGTSPEEGVGIAYAIAEEI
IRSKAFCFFATHFKELSTALPARYPNVVALRLETDVDEKQPDFSLTFRHKVRDGATPHTH
YGLELAKAVKLPSPVLYKARLVSLTLESLAEDGRKRSSEGKLVRRRRGLLELKTRLREIA
TGKTDDAGVLLAQLRQLQKETIEMLDETMDVVQDVEDGFEGEASRTEEAQEAEEEEEEAV
SNAGWMVTEIKPEDLSLAETAEEGTVAEEDEEDMLPFD