Protein Info for mRNA_6629 in Rhodosporidium toruloides IFO0880

Name: 14997
Annotation: KOG0538 Glycolate oxidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF01070: FMN_dh
  • amino acids 25 to 369 (345 residues), 345 bits, E=4.9e-107
• PF01645: Glu_synthase
  • amino acids 289 to 329 (41 residues), 20.7 bits, 2.2e-08

Best Hits

KEGG orthology group: None (inferred from 42% identity to aor:AOR_1_438194)

Predicted SEED Role

"L-lactate dehydrogenase (EC 1.1.2.3)" in subsystem L-rhamnose utilization or Lactate utilization or Respiratory dehydrogenases 1 (EC 1.1.2.3)

MetaCyc Pathways

• methylglyoxal degradation V (2/3 steps found)

KEGG Metabolic Maps

• Pyruvate metabolism

Isozymes

Compare fitness of predicted isozymes for: 1.1.2.3

Use Curated BLAST to search for 1.1.2.3

Protein Sequence (384 amino acids)

>mRNA_6629 KOG0538 Glycolate oxidase (Rhodosporidium toruloides IFO0880)
MAVPLPTPSTPLSSLLNLEDFERSAEATLKPKSWAYYASAADDGWTAEQSKAIWQHVRFR
PRVLRDVGGDVDLRVEIAGIESRLPFMVSPAAMGKLAHKDGELCIVKGAGRVGIPYAPSN
HASVSHRDLASAAVPSQSLFFQLYVHRERWRSEKQLAEAKELGYKAVIVTVDVAVPGNRE
LDLRTGLDENTVLLANPGIEVGKKAFAMATTSATIDASLSWKDLDWVKKASGGLPVLVKG
IHTVEDAVLAEQYGASGIFLSNHGGRQVNTASTPLEVLLEIRQSAPHLLASPSRFTVILD
GGLRRGTDIVKALCLGAHACSLGRPFMYSLVYGEDGVEKVARVLEEEVVRCCKLLGVRSV
KELRPQYVNARRVERAVFGSEARL