Protein Info for mRNA_6642 in Rhodosporidium toruloides IFO0880

Name: 15010
Annotation: KOG2684 Sirtuin 5 and related class III sirtuins (SIR2 family)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 568 PF02146: SIR2" amino acids 38 to 109 (72 residues), 28.5 bits, see alignment E=7.3e-11 amino acids 120 to 179 (60 residues), 28.3 bits, see alignment 8.3e-11 amino acids 221 to 333 (113 residues), 26.5 bits, see alignment E=2.9e-10

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (568 amino acids)

>mRNA_6642 KOG2684 Sirtuin 5 and related class III sirtuins (SIR2 family) (Rhodosporidium toruloides IFO0880)
MLTLELEDFASTSECTLEALAHVAVSLAESAQVVAAVGAGISTSAGIPDFRGFRGIYSSS
SPTSSLSSPHRPPSTPRSSQATKHLFSYSSLLHPESRSEHFRFMAELRKAARKAGKGKER
EDEAPTAFHGFMQRLERTGKLMRVWSQNVDGLEGRAGLDFVDFTDASLLDASPGDTSYDS
PDEESSSDYERPDWTPTRRARKCRRLSPLPLHPPLSSATSERGKVVALHGSLGEVVCGVC
DWREKWRKRHSKAVRKGRAIPCPQCRGRAHSRLQRSKRLVPPSPLSFLRPSILLYDDPIT
SHSSLSSSISSLAASDLSAGPDCLIVAGTSLRIPGFRRIVKDVARAVRARDGVCVFVNGE
KVGREWDEVFDYHFLGSTDSFALAISSFLDTFSPLPPPSPPSLSSSQLPSPPTILSPLPC
SPPLPTSSAASEAGWSIPHTPPSSVVELSSPCARREKKGKKKERGRKRRREAERAGPDGG
ERKKRRRRESEGGQRGRKGSSPPTPPSSMPTLPTSSPSSSAFSTASPNFRSDMSIAELLH
LVERRTRREARDRRRLSKRAKTSEVALE