Protein Info for mRNA_6684 in Rhodosporidium toruloides IFO0880

Name: 15052
Annotation: K04464 MAPK7 mitogen-activated protein kinase 7

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 469 PF00069: Pkinase" amino acids 44 to 339 (296 residues), 224.4 bits, see alignment E=1.7e-70 PF07714: Pkinase_Tyr" amino acids 45 to 249 (205 residues), 107 bits, see alignment E=1.1e-34

Best Hits

Swiss-Prot: 59% identical to SLT2_YEAST: Mitogen-activated protein kinase SLT2/MPK1 (SLT2) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

KEGG orthology group: K04464, mitogen-activated protein kinase 7 [EC: 2.7.11.24] (inferred from 68% identity to cnb:CNBH0400)

Predicted SEED Role

No annotation

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.11.24

Use Curated BLAST to search for 2.7.11.24

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (469 amino acids)

>mRNA_6684 K04464 MAPK7 mitogen-activated protein kinase 7 (Rhodosporidium toruloides IFO0880)
MSHPTSRSSPSHAPSPSQFIDPIHNIARTTFPVLAEPFLVDHNYEFVKELGQGAYGVVCS
ARNKLTGDQVAIKKVTKVFQKKILTKRALREIKLLHHFRGHKNITCLYDLDLVDPTNFDS
IYLYEECMEADLHAIIRSGQPLSDAHFQSFIYQTLCGLKYIHSAHVLHRDLKPGNLLVNA
DCELKICDFGLARGFDQDAAAADGQQQGFMTEYVATRWYRAPEIMLSFANYTTAIDIWSV
GCVLAELLGGRPIFKGKDYIDQLNIVLHFLGTPSDRTLRRVGSPRAQDYIRSLPYKPGVP
FVQLFPQANPLALDLLAKLLAFDPHERISCEDALLHPYLSVWHEPADEPTCPEKFDFGFE
EEETVDGMRRLIVEEVESFRRLVRPGMQQVPPPPSQQQAQGQNVQHGLAQRRQDPMPQLP
KRDDMLATPTNNGARYEEYGRVQQGGEGPVEEHPGMELDRELEYGVGGR