Protein Info for mRNA_6886 in Rhodosporidium toruloides IFO0880

Name: 15254
Annotation: K09493 CCT1, TCP1 T-complex protein 1 subunit alpha

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 560 TIGR02340: T-complex protein 1, alpha subunit" amino acids 20 to 553 (534 residues), 912 bits, see alignment E=6.5e-279 PF00118: Cpn60_TCP1" amino acids 40 to 546 (507 residues), 498 bits, see alignment E=1.4e-153

Best Hits

Swiss-Prot: 75% identical to TCPA_SCHPO: T-complex protein 1 subunit alpha (cct1) from Schizosaccharomyces pombe (strain 972 / ATCC 24843)

KEGG orthology group: K09493, T-complex protein 1 subunit alpha (inferred from 83% identity to uma:UM01279.1)

Predicted SEED Role

"Heat shock protein 60 family chaperone GroEL / Thermosome subunit" in subsystem GroEL GroES or Staphylococcal pathogenicity islands SaPI or Thermosome, archaeal

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (560 amino acids)

>mRNA_6886 K09493 CCT1, TCP1 T-complex protein 1 subunit alpha (Rhodosporidium toruloides IFO0880)
MASSLMFARDPRQSSGLLGTGERVSGAEVREQNVQAAVAIANIVRTSLGPHGLDKMLVDD
IGDVTISNDGATILQLIEVEHPAGRILVELAQQQDKEVGDGTTSVVIVAAELLRRANDLV
KNKIHPTTVITGYRLACKEAVRYLTEQLSVKVDQLGKECLINIAKTSMSSKIIGADDTFF
ANLAVDAMLAVKTINARGDVKYPVKAVNVLKAHGKSATESIYVKGYALNCTVASQAMKTR
ITGAKIACLDMNLQKTRMHLGVHITIDDPEQLEAIRKREYEITLERVRKILASGANVVLT
TKGIDDLCLKEFVEAGAMAVRRCKKEDLRRIAKATGATMVSSLANLEGEETFEASYLGQA
EEVVQERISDDELILVKGTKVVSSSSVILRGANDYLLDEMERALHDSLCAIKRTLESGSV
VPGGGAVETALSIYLENFATTLGSREQLAIAEFAAALLVIPKTLAVNAAKDSTELVAKLR
AYHNAAQSAPVGDPRRGLRYYGLDLMKGEVRDNVKAGVLEPMVSKVKSLKSALEACTALL
RIDDRITVPPEQKGEDPHGH