Protein Info for mRNA_6954 in Rhodosporidium toruloides IFO0880

Name: 15322
Annotation: K10591 NEDD4, RSP5 E3 ubiquitin-protein ligase NEDD4

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 820 PF00168: C2" amino acids 15 to 107 (93 residues), 75.8 bits, see alignment E=4.6e-25 PF00397: WW" amino acids 236 to 265 (30 residues), 41 bits, see alignment (E = 2.4e-14) amino acids 342 to 371 (30 residues), 47.8 bits, see alignment (E = 1.9e-16) amino acids 400 to 429 (30 residues), 41.1 bits, see alignment (E = 2.3e-14) PF00632: HECT" amino acids 517 to 819 (303 residues), 322.4 bits, see alignment E=5.6e-100

Best Hits

KEGG orthology group: K10591, E3 ubiquitin-protein ligase NEDD4 [EC: 6.3.2.19] (inferred from 68% identity to cnb:CNBL0210)

Predicted SEED Role

No annotation

Isozymes

Compare fitness of predicted isozymes for: 6.3.2.19

Use Curated BLAST to search for 6.3.2.19

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (820 amino acids)

>mRNA_6954 K10591 NEDD4, RSP5 E3 ubiquitin-protein ligase NEDD4 (Rhodosporidium toruloides IFO0880)
MSSGAAAPDPNRKRKIRVTIVAADSLAKRDVFRLPDPFAVMTVDGEQTMTTSAIKKTLNP
YWNESFDVDVKDSSVLTVQIFDQKKFKKKDQGFLGVINIPIAQAVDLDLGGEETFTRDLK
RSNDQLVVHGKLIVHVTTNLNGGARPATTAPLGSSSTAQTASGSGSPAPSPAPSTSGTPA
AAAITAPASPRPDAASPASTATPAPPATSAATPSAVPTSGSTTREFNSREDQYGPLPPGW
ERRVDHLGRTYYVDHTTRTTTWTRPNRDQPASARPNGATSTATGSQASSAARAGGRTTAD
EFLGTGDSQSATPAQPSTPTSATAAAAAGHASSATTVGSGPLPAGWEQRFTPEGRPYFVD
HNTRTTTWVDPRRQQLLRVMGPNGNNLTVQPQSVSQLGPLPSGWEMRLTSTARVYFVDHN
TKTTTWDDPRLPSSLDQNVPQYKRDFRRKLIYFRSQPALRPSPGQCHVKVRRTHIFEDSY
AEIMRQTPNDLKKRLMIKFDGEDGLDYGGLSREFFFLLSHEMFNPFYCLFEYSAHDNYTL
QINPNSSVNPEHLNYFKFIGRVLALAVFHRRFLDAYFITALYKMILKKKITLADMESVDA
EMFRSLTWILENDITDVIENTFSAEDDRFGETVTIDLKPGGRDIEVTNDNKKEYVQLIVE
WRIQGRVKDQFSAFLSGFNELIPQELINVFDERELELLIGGMSEIDVDDWVKHTDYRGFT
QSDEVVQWFWKAVKSWPTEKKSRLLQFATGTSRIPVNGFKDLQGSDGPRRFTLEKSGEIT
QLPKSHTCFNRLDLPPYPDYETLEKKLTIAIEETMGFGNE