Protein Info for mRNA_6960 in Rhodosporidium toruloides IFO0880

Name: 15328
Annotation: K01469 OPLAH, OXP1, oplAH 5-oxoprolinase (ATP-hydrolysing)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 753 PF05378: Hydant_A_N" amino acids 12 to 246 (235 residues), 184.3 bits, see alignment E=1.8e-58 PF01968: Hydantoinase_A" amino acids 265 to 569 (305 residues), 331.2 bits, see alignment E=5.7e-103

Best Hits

KEGG orthology group: K01469, 5-oxoprolinase (ATP-hydrolysing) [EC: 3.5.2.9] (inferred from 59% identity to scm:SCHCODRAFT_82383)

Predicted SEED Role

"5-oxoprolinase (EC 3.5.2.9)" in subsystem Glutathione: Biosynthesis and gamma-glutamyl cycle (EC 3.5.2.9)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.5.2.9

Use Curated BLAST to search for 3.5.2.9

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (753 amino acids)

>mRNA_6960 K01469 OPLAH, OXP1, oplAH 5-oxoprolinase (ATP-hydrolysing) (Rhodosporidium toruloides IFO0880)
MSPANIPDRSIKIAVDRGGTFSDVHASWPVEGQKERKEIILKLLSSDPGHYKDAPREGVR
RVLEIATGNTYKREDRLPVDKIDSIRLSTTVATNALLERKGAKHALVVTKGFKDLLLIGN
QSRPRIFDLDIKRPSVLYSSVLEVDERVTLLGYTSDPKHPERAVKFDEEGKVAKGYDGAE
HAEGSVVKGMSGEAVHILKKVDEEQVERDLRKLYDDGIRVLAIVLMHAFTYPEHEQQIAR
IAQKIGFEHISLSSSSLPMIRIVARGMSTTADAYLTPVLREYIDGFFSGFDESLRETSYR
ETKSKEQAQRETTVEFMRSDGGLTDVSDFSGLKSILSGPAGGVVGYALTSWEKGGRPVVG
LDMGGTSTDVSRFDGEYETVFETTTAGITVMSPQLSINTVAAGGGSRLFWRNGMFVTGPE
SAGSHPGPACYRKQGYPAVTDANLVLGRLLPSHFPQIFGASEDQPLDIDASRSALEELRK
QINDETGNNLSLDEVAFGFIKVANETMCRPIRSLTEARGYDTSKHILSCFGGAGGQHACA
LAETLGITTILIHRFSSVLSAYGMALAERVFERQEPSSETWGADGSQGRLQARLDALSQQ
VKKTLSQQGFADDRIEVQQFLNCRYQGTDSALFTRKPDDGFDFAKAFAANYKQEFGFSMD
APIIVDDVRVRGVGKSFDSLGKSVFEEVRELEFKPLAREAEKDGQTSKCHEKASVYFEDT
GRVDVPVYLLENLEAGDEAEGPGASRSSCPSTR