Protein Info for mRNA_6974 in Rhodosporidium toruloides IFO0880

Name: 15342
Annotation: K17686 copA, ATP7 Cu+-exporting ATPase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1019 transmembrane" amino acids 207 to 231 (25 residues), see Phobius details amino acids 243 to 265 (23 residues), see Phobius details amino acids 282 to 302 (21 residues), see Phobius details amino acids 314 to 332 (19 residues), see Phobius details amino acids 469 to 492 (24 residues), see Phobius details amino acids 508 to 531 (24 residues), see Phobius details amino acids 863 to 885 (23 residues), see Phobius details amino acids 892 to 914 (23 residues), see Phobius details TIGR00003: copper ion binding protein" amino acids 33 to 96 (64 residues), 43.5 bits, see alignment 7.4e-15 PF00403: HMA" amino acids 35 to 95 (61 residues), 55.7 bits, see alignment 1.1e-18 amino acids 125 to 179 (55 residues), 42 bits, see alignment 2.1e-14 TIGR01525: heavy metal translocating P-type ATPase" amino acids 280 to 911 (632 residues), 619.3 bits, see alignment E=1.9e-189 TIGR01494: HAD ATPase, P-type, family IC" amino acids 322 to 585 (264 residues), 122 bits, see alignment E=5.8e-39 amino acids 709 to 881 (173 residues), 148 bits, see alignment E=8e-47 PF00122: E1-E2_ATPase" amino acids 352 to 546 (195 residues), 163.1 bits, see alignment E=1.1e-51 PF00702: Hydrolase" amino acids 565 to 817 (253 residues), 142.9 bits, see alignment E=3.5e-45 PF08282: Hydrolase_3" amino acids 785 to 847 (63 residues), 21.5 bits, see alignment 3.7e-08

Best Hits

Predicted SEED Role

"Lead, cadmium, zinc and mercury transporting ATPase (EC 3.6.3.3) (EC 3.6.3.5); Copper-translocating P-type ATPase (EC 3.6.3.4)" (EC 3.6.3.3, EC 3.6.3.4, EC 3.6.3.5)

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.3, 3.6.3.4, 3.6.3.5

Use Curated BLAST to search for 3.6.3.3 or 3.6.3.4 or 3.6.3.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1019 amino acids)

>mRNA_6974 K17686 copA, ATP7 Cu+-exporting ATPase (Rhodosporidium toruloides IFO0880)
MASSAPLLDNADDLDVLSFGSKGKEKMTGLETVQLKVEGMTCGACVASIESGLKDQEGIA
SVKVALLAERAVVEYDPDRWTPAKLAEEIEDMGFEATPIEPVVADTVQLQVYGMTRVLDP
FCRECGACVASIENALRSAPGIISAVVSLATERASVTYDPSVVAGPRDIVELIEDVGFDA
TLASDENSAMQLQSLARTKEIQEWKHAFVRSFSFGLPVFLISMILPMIPFLRPLVNFPIL
RGVYLGDTVCLFLTIPVQFGIGLRFYRSAWRAIKHKSATMDVLVVLGTSAAFLYSVLVML
FAPFASDPSFHPKVFFDTCTMLITFISFGRYLENVAKGQTSTALSRLLSLAPSQAIIYTD
AECTKEKKVPTELIQVGDVVKVVPGDKIPADGVVIRGESAVDESMVTGEVVPVAKSTEST
VIGGTVNGKGTFDMKVTRAGKDTALSQIVHLVEEAQTSKAPIQAFADTVAGYFVPVVISL
GLFTFVAWMVIAHLSPRLPHVFEEHGATKFMVCLRLCISVIVVACPCALGLSTPTAVMVG
TGVGAQNGILIKGAGPLEASHRVDRIVLDKTGTVTLGKLDVVGVRWVERTGLMETEELGS
HIGWQEDAILLFAAAETKSEHPLAKAVAQWGLRQLGLSEVPSTLEVKAFESFTGRGIRCD
VSGHFPSLSPTAGTGRSTHSIEIGNVDFLTQQCSIALPRAHESFREREESLGRTCILVAV
DRQLACIVSLADQIKPEARQAIDALRWMGIEVLLATGDQERTARAIADEVGIAHEDVQAG
MSPNGKKALVEKLRHQGHRVAMVGDGINDSPALAAADVGIALCTGTDIAMEAADIVLMKA
DLLDVVAALDLSRRIFRQIRLNFLWATIYNLVGVPLAMGLFLPWGLHLHPMMAGAAMAFS
SVSVVASSLTLRFWRRPRLARRPDDPAFDKGEGALSELTGGVVEMLKAGWETFFVDRSGR
RHRSGGRFRQLLRTERSHSEYGLLGTDSSPEDDAVMMEEGIPLAGAASPMVRNPGLMGA