Protein Info for mRNA_6978 in Rhodosporidium toruloides IFO0880

Name: 15346
Annotation: KOG1014 17 beta-hydroxysteroid dehydrogenase type 3, HSD17B3

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 245 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details PF00106: adh_short" amino acids 8 to 199 (192 residues), 112 bits, see alignment E=4e-36 PF08659: KR" amino acids 11 to 159 (149 residues), 31 bits, see alignment E=3.6e-11 PF13561: adh_short_C2" amino acids 14 to 225 (212 residues), 99.6 bits, see alignment E=3.3e-32

Best Hits

KEGG orthology group: None (inferred from 51% identity to ani:AN2694.2)

Predicted SEED Role

"Short-chain dehydrogenase, associated with 2-hydroxychromene-2-carboxylate isomerase family protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (245 amino acids)

>mRNA_6978 KOG1014 17 beta-hydroxysteroid dehydrogenase type 3, HSD17B3 (Rhodosporidium toruloides IFO0880)
MAAQSTRKLAVVVGAGPGLGASLARAFAHRNHAVAVLARSEKTVQSVAEDIRKNGGDAAP
FACDVTKRDSLDAAFAAIKKQWPDHQLKAALFNANSPFIMKPFLELKEEDVKPGVDVNFY
GAFHFAQVTIPLMLEAGGGFLGITGATAALKGSAKFAALAPGKFALRGLAQNLAREFGPK
GVHVSHIIVDGIIETDRVKGMMGEAKQPDSRLQPDAIADTYVHLAEQPRNCWAFELDLRP
SVEKW