Protein Info for mRNA_7017 in Rhodosporidium toruloides IFO0880

Name: 15385
Annotation: K03574 mutT, NUDT15, MTH2 8-oxo-dGTP diphosphatase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00293: NUDIX
  • amino acids 6 to 127 (122 residues), 82 bits, E=2.1e-27

Best Hits

Swiss-Prot: 40% identical to NUDT1_ARATH: Nudix hydrolase 1 (NUDT1) from Arabidopsis thaliana

KEGG orthology group: None (inferred from 57% identity to ang:ANI_1_2030094)

MetaCyc: 40% identical to 8-oxo-dGTP pyrophosphohydrolase (Arabidopsis thaliana col)
H2NEOPTERINP3PYROPHOSPHOHYDRO-RXN [EC: 3.6.1.67]; RXN-11396 [EC: 3.6.1.67, 3.6.1.55]; 3.6.1.- [EC: 3.6.1.67, 3.6.1.55]

Predicted SEED Role

No annotation

MetaCyc Pathways

• 8-oxo-(d)GTP detoxification I (4/4 steps found)
• 6-hydroxymethyl-dihydropterin diphosphate biosynthesis I (3/5 steps found)
• superpathway of tetrahydrofolate biosynthesis and salvage (8/12 steps found)
• superpathway of tetrahydrofolate biosynthesis (6/10 steps found)
• superpathway of chorismate metabolism (28/59 steps found)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.6.1.55 or 3.6.1.67

Protein Sequence (151 amino acids)

>mRNA_7017 K03574 mutT, NUDT15, MTH2 8-oxo-dGTP diphosphatase (Rhodosporidium toruloides IFO0880)
MAQHVKVGVGCFLLNSRGEFVVGVRKGSHGAGCLQLPGGHLDFGETPEACAVREVAEETG
LAVREADVRFLTATNDIFEADKKHYITMFVVCRVADDADPQVLEPEKCERWEWHTWEQLK
ELVSDPSNRLFLPLRNLFLQRPDADPRRLVL