Protein Info for mRNA_7114 in Rhodosporidium toruloides IFO0880

Name: 15482
Annotation: K00383 GSR, gor glutathione reductase (NADPH)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 490 TIGR01421: glutathione-disulfide reductase" amino acids 18 to 490 (473 residues), 639.1 bits, see alignment E=2.7e-196 PF07992: Pyr_redox_2" amino acids 19 to 356 (338 residues), 226.4 bits, see alignment E=2.4e-70 PF01134: GIDA" amino acids 20 to 78 (59 residues), 22.4 bits, see alignment 3.1e-08 PF00890: FAD_binding_2" amino acids 20 to 56 (37 residues), 21.5 bits, see alignment 5.9e-08 PF12831: FAD_oxidored" amino acids 20 to 81 (62 residues), 38.1 bits, see alignment E=6.6e-13 PF13450: NAD_binding_8" amino acids 23 to 57 (35 residues), 27.4 bits, see alignment 1.6e-09 PF13434: K_oxygenase" amino acids 154 to 239 (86 residues), 22.7 bits, see alignment E=2.6e-08 PF13738: Pyr_redox_3" amino acids 158 to 340 (183 residues), 40.5 bits, see alignment E=1.1e-13 PF00070: Pyr_redox" amino acids 200 to 270 (71 residues), 72.4 bits, see alignment E=1.9e-23 PF02852: Pyr_redox_dim" amino acids 377 to 489 (113 residues), 112.5 bits, see alignment E=6.2e-36

Best Hits

Predicted SEED Role

"Glutathione reductase (EC 1.8.1.7)" in subsystem Glutathione: Redox cycle (EC 1.8.1.7)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.8.1.7

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (490 amino acids)

>mRNA_7114 K00383 GSR, gor glutathione reductase (NADPH) (Rhodosporidium toruloides IFO0880)
MAPVPFKSQAKETGGENHYDLIVIGGGSGGLGAARRAAQYGARVAIIEETWRLGGTCVNV
GCVPKKVMWHAADLAEKMHQANAYGFTVPEGATKIDWSTIKRKRDAYIERLNGIYERNVE
KDGVDYITGHAAFVDKKTIKVLPTYPESKAHGGSDVERQYTAERFVIAVGGTPTLPTDIP
GYEYGFHSDGFFYLEELPKRAVVVGAGYIAVELAGIFHTLGAETHLVIRRDKVLKAFDPM
LQDTLQQYMIKTGIHIHTNSHVTKVTTDVEKPDLYKPFPKVIHTDKGEEIGADVLLWAIG
RHSLTDNIGAEKIGLKLEKNGDIPVDEYQATNVDNVFAIGDVGGKALLTPVAIAAGRRLS
NRLYGGVKDDKLSYENIPTVVFSHPTIGTVGLTEPEAREKFGDENIKIYTSTFTALYFSM
MDPEHKEPTAMKLVCAGKEEKVVGLHTIGQGSDEMLQGFALAVTMGATKKDFDSVVPIHP
TSSEELVTMR