Protein Info for mRNA_7149 in Rhodosporidium toruloides IFO0880

Name: 15517
Annotation: K12733 PPIL1 peptidyl-prolyl cis-trans isomerase-like 1

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 158 PF00160: Pro_isomerase" amino acids 5 to 154 (150 residues), 180.8 bits, see alignment E=1.2e-57

Best Hits

Swiss-Prot: 73% identical to PPIL1_CRYNB: Peptidyl-prolyl cis-trans isomerase-like 1 (CYP1) from Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)

KEGG orthology group: K12733, peptidyl-prolyl cis-trans isomerase-like 1 [EC: 5.2.1.8] (inferred from 79% identity to lbc:LACBIDRAFT_191564)

Predicted SEED Role

"Peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8)" in subsystem Queuosine-Archaeosine Biosynthesis (EC 5.2.1.8)

Isozymes

Compare fitness of predicted isozymes for: 5.2.1.8

Use Curated BLAST to search for 5.2.1.8

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (158 amino acids)

>mRNA_7149 K12733 PPIL1 peptidyl-prolyl cis-trans isomerase-like 1 (Rhodosporidium toruloides IFO0880)
MPQAVLLQTNLGPITFELYDQHAPKTCRNFVELSKRGYYQGTVFHRIIADFMIQGGDPTG
TGRGGTSIYGDRFEDEIHPELRFTGAGILAMANSGPNTNGSQFFITLAPTPHLERKHTIF
GRVSSGMQVVQRLGAVATDAEDRPREEMKIIKASVVDV