Protein Info for mRNA_7172 in Rhodosporidium toruloides IFO0880

Name: 15540
Annotation: K01408 IDE, ide insulysin

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1071 PF00675: Peptidase_M16" amino acids 73 to 205 (133 residues), 135.2 bits, see alignment E=2.8e-43 PF05193: Peptidase_M16_C" amino acids 235 to 408 (174 residues), 63 bits, see alignment E=5.7e-21 amino acids 709 to 888 (180 residues), 37.3 bits, see alignment E=4.6e-13 PF16187: Peptidase_M16_M" amino acids 419 to 705 (287 residues), 303.5 bits, see alignment E=2.2e-94

Best Hits

Predicted SEED Role

"Protease III precursor (EC 3.4.24.55)" (EC 3.4.24.55)

Isozymes

Compare fitness of predicted isozymes for: 3.4.24.55

Use Curated BLAST to search for 3.4.24.55

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1071 amino acids)

>mRNA_7172 K01408 IDE, ide insulysin (Rhodosporidium toruloides IFO0880)
MTITDSSYKPHAPYAFVTKPGSAIDHLDKQDWDIVKGREGLPAYAVYRKDIEKSQNDDRV
YRLIMLENGLEALVVSDPKTDKAAAAMDVKVGHLSDPEDLPGLAHFCEHLMFMGTEKYPA
ENDYTEFLTQHSGSSNAFTGMDQTNYYFDVAPQHLAPALDRFAQFFISPLFDSSCTEREA
NAVHSENSKNLQNDMWRFYQLDKSTSSRKHAFWRFGTGNRETLWDEPRAKGVDVRQRLID
WCEKHYSANTCKLAVVSKDTLDETVKLVVSQFASVPNRHITPPEFPGSPLTSSELGQTLF
IKSIRDTRFLELTFPFPDESELYASKPGSFLSHLIGHEGKGSVLSLLKKRGWANGMSAGA
GNGAAGFEFFKVSVDLTKEGLEHYEDVAASIFAYISLLRSTPPAEWAFLEVAQLSQLAFR
FKEKSPPSSTASRLAMILSKPYPRDKVLSAPWICTEWYPKKVEEFLDLMTPEKCRIFVSA
QEEIEGRKYELREEWYGTEYTVERMSDKILNSGKSASEYPELALPEPNALVPQNLEIKNK
VEVPEPARRPLNLRNTPVSRVWHKKDDRWWIPRAGVFFLFRSPLIDSSALTAVQTRLFTE
LVRDSLQEYAYDAELAGLSYNFDQQADGILLSADGYNDKLPLLIEVIVKRMKEYKVDEKR
FAIVADMIRRMYQNFRLEQPYQHVGFDAAHLTQAVSYTVDEKLKALDQITPANLQSHIAA
LFSRMHIESLVHGNVLRDEALALAKTVEDTFKPEALTVEELKSRQALIIPEGKWLARRPV
DNPANANSAVEQFTYVGDIYDDVLRAKLSLFGTMVSEPLFDDLRAKQQLGYIVSSGARKS
IAYMGLRVIVQSERDSAFVESRIDAFWDEYKTRLDEMSEEEFEKYKATVISRKLEDFKNL
WQESSAMWINIHAGWYDFEQRFRDAELVKQLSKSDIISFYHTYFFDTPERRIRRLSVHLD
SQRLTVEQCASLGPVLAEMQVQVDPEQLGHFATSRPTVEQAKAFAEQFLRAQGRGDEDVK
KVVEEIERLGKPKDLEGYQVIEDREQWRQQQERAPHAHPVAEYSDLFPAKL