Protein Info for mRNA_7209 in Rhodosporidium toruloides IFO0880

Name: 15577
Annotation: K01408 IDE, ide insulysin

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1051 PF00675: Peptidase_M16" amino acids 53 to 187 (135 residues), 132.3 bits, see alignment E=2.2e-42 PF05193: Peptidase_M16_C" amino acids 218 to 395 (178 residues), 59.2 bits, see alignment E=8.8e-20 amino acids 707 to 870 (164 residues), 38.4 bits, see alignment E=2.1e-13 PF16187: Peptidase_M16_M" amino acids 402 to 686 (285 residues), 262.2 bits, see alignment E=8.7e-82

Best Hits

Predicted SEED Role

"Protease III precursor (EC 3.4.24.55)" (EC 3.4.24.55)

Isozymes

Compare fitness of predicted isozymes for: 3.4.24.55

Use Curated BLAST to search for 3.4.24.55

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1051 amino acids)

>mRNA_7209 K01408 IDE, ide insulysin (Rhodosporidium toruloides IFO0880)
MQRATQPFDFGRLGSDWREEDQGDFAILEKEIEVSPNDDRKYRLIVLRNGLKALLISDPQ
TDKAAAALGVQVGHLNDPDDLPGLAHFCEHMLFLGTEKYPEEAEYKTYLSRNAGSSNAYT
SRKSTVYHFECSPASLPGALSRHAQFFTSPLFDASCTERERNAVDSEFRRNLQLDTRRLF
QLGKATSSREPGSVYWKFGTGSKESLWQEPRARGIDVRDRLLEWYSKHYSANLMSLVVLG
NQSLDELTQLVLQEYSDIPNLNLEATYFTVPPISPAIAGQQISYRTVKDTPKLRIEFGMP
DLRRHWRTKPGRFLSHYLGHEGEGSVLAVLKSLGWATSLSASSGGGARGFDFFRVEISLT
ATGLQHYKEAIALVFRYVELLKSTAPQRWAFDEMQQLGKIDWRWKEKGQPQSTTRNLASQ
LGETLYDPDKLLVGPWFSTEWDESLIKETLDNLRADNCRVFVGSKEPLPGREFWKEREKY
YGTEYDIFPLDVDSLASTSASSLALPGHNIFVPEKLDLLREKPSSDPAKRPSLIRKTPRS
RLFFKADDRWCIPKGSAFFIFRSPFADTSPRNAILTQLFTSLVEESLTKYSYDATLAGLH
YAFGTESGGFSLIVSGYTEKLPLLASVVLDTAKDFQIADKDFEIVHDRLTRAYANAKLSN
PSGLADAEVRRLTRQTYWTWDERLEALQGVALADVRQHAQHLLAKYSLDALVTGNFAGTD
AVKMVETLEGKLDAQPADSSETDYHRALKLPPGSSTVYRPLVPSPENVNSAVSAYYDVGP
ASDHELLAKLSLFAQLAKVPVFSTLRTKEQLGYIVSSGSWVTNAYAGFRVVVQSERSPEY
VDERIDALWSTFAERVQDMSEEEFEKERESLVHKLLEKPKTLGQESNRYWAEVSTGELDF
GYRERQAKLVRRLSRADVLAFFDRFISPSSASRTKLAILYRSQRLQLVDLAPLFEAVKAA
APDKADEASTFAQTKPTIAQLEAFVKEDYSNDSAVLAALERVKEPRPLPEGPEGTKELRE
EDIEPFRRGLERAEGYRPVSNDEDLQAAAHL