Protein Info for mRNA_7488 in Rhodosporidium toruloides IFO0880

Name: 15856
Annotation: K00558 DNMT1, dcm DNA (cytosine-5)-methyltransferase 1

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1107 transmembrane" amino acids 581 to 594 (14 residues), see Phobius details PF00145: DNA_methylase" amino acids 514 to 873 (360 residues), 73.6 bits, see alignment E=1e-24

Best Hits

Predicted SEED Role

"DNA-cytosine methyltransferase (EC 2.1.1.37)" (EC 2.1.1.37)

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.1.1.37

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1107 amino acids)

>mRNA_7488 K00558 DNMT1, dcm DNA (cytosine-5)-methyltransferase 1 (Rhodosporidium toruloides IFO0880)
MFFPNAFRTENEEVVRQAVAEEKKRDARLLERYRSIVQHDVKLWFGLIVYFHRKRAKPHA
LGPSPLQAHVLWFATAATIRSLGPYLPPRQLLTLDICDDISACTLLRKVPFQFVKPAAAT
RSSSSIWPKTGFFSWALYNDEDGSFRDVDPAFLAVSGNGASVDNSATDRSKLFPHCDKRG
RPPCPSCETTFESNYRTKPEGSRRALRAIRIDGGFEIDRVPYHPGDFIYVVPVEDSAGDD
DADESDKHRPAAPDPRPYRLAQIVTVGDDADDADNLDEVDEVDKIKVKWLTRASDVPERL
RPSGGFLSEREVFFTDAPPYTLATADISKKFSLVQLDIADDEDAALVIARLESSSPDAFY
TRFRLVRKPGDPGRYGEDGEVWPIVDSHGFFYGEYGFEAVKLENGALQTCEACQTTFDRK
TAERRAVLQATSRATLNHLALYAGGGLLDRGLEEGCPILAVKHAVEKHAPAASCMRSNAL
HSLETLETTVSNVAEAAFYGIGVESGDIPPVGKVYSIAGGAPCQGFSQANHYKRIDDLRT
LEPFVFLSTLAVYRPPTAIFENVAAFRRHALPLPGSRSGSFFQLFIAVCLWLGYQVRWTL
VDSAGFGVPQHRRRLIVQLAASGFPLPDAPNPTHAVSNSVVNFNHRLTEEDTPQDFGPVF
APHKPVTIAAAIDDLPSFDTEIPNSEYVQRTYGIAWGDSEGRYRSAPRTSAQLRFRTMIS
PDGDTVTFTREPTHHVCRSVNKVVAERLRALKVIKADGSGGNHLDFKGKPFYAEPPAWVT
RKAAKLYFWWRRLMRNSTLSPLRTSFNLDGASHGERIHYNQARGLSLREMLRAQDFYELN
FSHATGDESFEEALRVIGNGVPVPLAAAYGRALLDKLIPIVLDWRAKGAKGDLWHSIWLD
LGGERLRATAAKKEGLPAHFDAAHIKEMSVEVVGAKEVADVEWMDVQEDDSDDDLYAYPE
PSTPPPSTPKPASKPSSQRHNFARKSAARVSPIRTLQRTSTSQSSGSSSSNASGWQFGRE
DTDQTRLTSVETGPAAQAQQAKRRRTQSREEEKDEQAKMAPQVMDIDSDDDEEEDVVIVS
DSDDEPIVKEKGPPAVITIEDSSDEDD