Protein Info for mRNA_7540 in Rhodosporidium toruloides IFO0880

Name: 15908
Annotation: K01012 bioB biotin synthase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR00433: biotin synthase
  • amino acids 59 to 359 (301 residues), 376.6 bits, E=4.3e-117
• PF04055: Radical_SAM
  • amino acids 95 to 252 (158 residues), 62.6 bits, E=6.5e-21
• PF06968: BATS
  • amino acids 269 to 360 (92 residues), 68.5 bits, E=4.6e-23

Best Hits

KEGG orthology group: K01012, biotin synthetase [EC: 2.8.1.6] (inferred from 68% identity to lbc:LACBIDRAFT_379847)

Predicted SEED Role

"Biotin synthase (EC 2.8.1.6)" in subsystem Biotin biosynthesis (EC 2.8.1.6)

MetaCyc Pathways

• biotin biosynthesis from 8-amino-7-oxononanoate I (4/4 steps found)
• biotin biosynthesis I (11/15 steps found)
• biotin biosynthesis from 8-amino-7-oxononanoate II (3/4 steps found)
• biotin biosynthesis II (4/6 steps found)
• biotin biosynthesis from 8-amino-7-oxononanoate III (3/5 steps found)

KEGG Metabolic Maps

• Biotin metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.8.1.6

Protein Sequence (409 amino acids)

>mRNA_7540 K01012 bioB biotin synthase (Rhodosporidium toruloides IFO0880)
MPAGQRTLLASLRAATRPQRRPHPSLALARSIPTATIQTRSLASQVDTRQGWTREQVQEV
YDSPLMELIFRAASVHRLNHPPDQVQLCTLLNIKTGGCSEDCSYCAQSSKYADKVGLKAE
KLTDVETVLAEARKAKENGSTRFCMGAAWRDMSGRKRGFERILKMVEGVRAMDMEVCTTL
GMLSPEQAQKLKEAGLTAYNHNLDTSREYYPKVITTRKYDERLETIEAVRSAGISVCSGG
IIGLGENDGDRVGLIYEMSQLPEPPESFPVNALVAIPGTPLEQNERVTIQELLRTIATAR
IVLPTSIIRFAAGRISYTETEQAMAFMAGANAIFTGERMLTTPTSGWDEDHAMLGRWGLK
GMGSFESTTVRMKEDKRALEATEARRSSVGRQGEVVGESQAAATQTVAA