Protein Info for mRNA_7566 in Rhodosporidium toruloides IFO0880

Name: 15934
Annotation: K12347 SLC11A, NRAMP natural resistance-associated macrophage protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 638 transmembrane" amino acids 149 to 165 (17 residues), see Phobius details amino acids 181 to 201 (21 residues), see Phobius details amino acids 231 to 250 (20 residues), see Phobius details amino acids 270 to 291 (22 residues), see Phobius details amino acids 304 to 325 (22 residues), see Phobius details amino acids 348 to 369 (22 residues), see Phobius details amino acids 541 to 566 (26 residues), see Phobius details amino acids 595 to 616 (22 residues), see Phobius details PF01566: Nramp" amino acids 170 to 380 (211 residues), 162.3 bits, see alignment E=8.8e-52 amino acids 532 to 629 (98 residues), 69.1 bits, see alignment E=1.8e-23

Best Hits

Predicted SEED Role

"Manganese transport protein MntH" in subsystem Transport of Manganese

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (638 amino acids)

>mRNA_7566 K12347 SLC11A, NRAMP natural resistance-associated macrophage protein (Rhodosporidium toruloides IFO0880)
MQGLAPASQGTHDTPSTPDTRTDPNQLERDHLDRNPAVISGHSDALTRAAGDEIELADSE
QVPEVDARSRDAGRDEGGEDGVVGKDGSERDLAGGGKSSRSPSPGPRKACQHASTSQGPS
RTPSDLEAGSPLPSSRESVVKKATNALKRHAAFVGPGVIASVAYLDPGNWSTDLAAGSQF
GYSHLFVIFFAGMMALLFQVLSTRLGCVSDYDLATHCRFALYDRPSPYKLYYRWLLLYPL
YVLAEIGIVMTDLAELLGSAIAINLLIPRIPLWACVLLTSLDVFLILLLFNQYPTRTVTR
SMRLFELLIGVLVIVVLGSFVAMIVKVGPVWKDVFRGYVPGSGIVGNGGIYIAVGIVGAT
VMPHAFYIGSKMATMRRLKPEDYGEVSPPSSRGLNSDDYDESKELKPSSASTNTAVEPER
EVEDSPARPRGRFASLLPSHLRPARTRSSPTRPRAYFPSIHLPQPVSLGHIGFDLGALSR
ARTRSRSPATERRRRLTNVREEGEEEKTEAPMDEVAKTHRIRPRPTLACVRAHLTHASID
VAFSLVGFALVVNSCILILGAAVFYYGDGRAQGRDAGGVSDLFDAYELVKEYLGQAFAYL
FAIALLAAGQSASLTVTLSGQIVSEGCVALLFSPSCSR