Protein Info for mRNA_7710 in Rhodosporidium toruloides IFO0880

Name: 16078
Annotation: K06067 HDAC1_2 histone deacetylase 1/2

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 572 PF00850: Hist_deacetyl" amino acids 39 to 328 (290 residues), 271.3 bits, see alignment E=6.5e-85

Best Hits

Predicted SEED Role

"NAD-independent protein deacetylase AcuC" in subsystem Pyruvate metabolism II: acetyl-CoA, acetogenesis from pyruvate

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (572 amino acids)

>mRNA_7710 K06067 HDAC1_2 histone deacetylase 1/2 (Rhodosporidium toruloides IFO0880)
MASTDQPSLFSPAPGGPDKRTVAYFYDDDVGAYAFNLVHPMKPHRIKMAHNLITNYGLDK
HMDVLKPDRCPPHEMTRFHTDEYIDCLARVTPETFDEMTGHGQRFLIGEDCPPFEGLFEF
CSISAGGSLSAARRLIEGKADVAVNWAGGLHHAKKREASGFCYINDIVLAILELLRYHSR
VLYIDIDVHHGDGVEEAFYTTDRVMTASFHKFGDFFPGTGAEGDKGRGRGKGYAVNFPLK
DGIDDESYRSVFRPIMQAIMDWYRPGAVVLQCGADSLASDKLGSFNLSMNGHASCVAFMR
TFNVPLIIVGGGGYTIRNVARTWAYETGIACGVQMQRDLPFNEYIEYFGPEFKLDVPSNN
MDNANSREYLDKIVASILEGLRNLPFAPSSQLHQVGADLPPLSTDTTDDEADSDLDVRLS
SRIRSTARAATRLSAAAGGPGAHLEAEYESDDEDPDSHWRRKRRLAESYISSASQRRRED
LRERKRALAEKLAAAEDECAAGMMDVDGDEAEHEARRPVKRTFFKPSRLDVKTLLKGPDP
GLRRLGIAESDILAAGPAGNGITREWDSVYGL