Protein Info for mRNA_7743 in Rhodosporidium toruloides IFO0880

Name: 16111
Annotation: K09569 FKBP2 FK506-binding protein 2

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 159 signal peptide" amino acids 1 to 36 (36 residues), see Phobius details PF00254: FKBP_C" amino acids 58 to 147 (90 residues), 115.9 bits, see alignment E=4.3e-38

Best Hits

Swiss-Prot: 57% identical to FKBP2_MOUSE: Peptidyl-prolyl cis-trans isomerase FKBP2 (Fkbp2) from Mus musculus

KEGG orthology group: K09569, FK506-binding protein 2 [EC: 5.2.1.8] (inferred from 53% identity to ure:UREG_02354)

Predicted SEED Role

"FKBP-type peptidyl-prolyl cis-trans isomerase FkpA precursor (EC 5.2.1.8)" in subsystem Peptidyl-prolyl cis-trans isomerase or Potassium homeostasis (EC 5.2.1.8)

Isozymes

Compare fitness of predicted isozymes for: 5.2.1.8

Use Curated BLAST to search for 5.2.1.8

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (159 amino acids)

>mRNA_7743 K09569 FKBP2 FK506-binding protein 2 (Rhodosporidium toruloides IFO0880)
MAARHRVSNRTWLAMLSVGVALLGFSSYSAMGAAAQSVPESTAGLKIDTTYKPTPCYIKS
QKGDSLAMHYDGRLDSGKEFDSSRKRGQPFVFTLGKGMVIKGWDNGLLDMCPGEKRTLTI
PPELGYGSRGVGPIPGGATLVFDVELLDIKNRKPGKEEL