Protein Info for mRNA_7814 in Rhodosporidium toruloides IFO0880

Name: 16182
Annotation: K01620 ltaE threonine aldolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF01212: Beta_elim_lyase
  • amino acids 2 to 270 (269 residues), 225 bits, E=1.3e-70

Best Hits

KEGG orthology group: K01620, threonine aldolase [EC: 4.1.2.5] (inferred from 51% identity to cci:CC1G_04438)

Predicted SEED Role

"Low-specificity L-threonine aldolase (EC 4.1.2.48)" (EC 4.1.2.48)

MetaCyc Pathways

• glycine biosynthesis IV (1/1 steps found)
• L-threonine degradation IV (1/2 steps found)
• superpathway of L-threonine metabolism (11/18 steps found)

KEGG Metabolic Maps

• Glycine, serine and threonine metabolism

Isozymes

Compare fitness of predicted isozymes for: 4.1.2.48, 4.1.2.5

Use Curated BLAST to search for 4.1.2.48 or 4.1.2.5

Protein Sequence (366 amino acids)

>mRNA_7814 K01620 ltaE threonine aldolase (Rhodosporidium toruloides IFO0880)
MPTDEMFDLMRDASRGDDVYGEDQATNDLQDKIAKMAGKEAGLFCVSGTMTNQLAIRTHL
TQPPHSIILDARSHVHLYEAGGVAMHSQASSHAVPPRNGHHLTLEEILDNAVFGEDIHSA
PTKLVSLENTLSGMVFPQEEIVRISDCMRSNGIIMHCDGARMWEAAVKTGLSLEELCRPF
DTVSLCLSKGLGAPVGSVLVGPRKFIEKVKWFRKAFGGGIRQCGSLAVAADYCVDNHFLK
LKGTHELASYLAKSLADLGAQLLLPVETNMLWLDPSSLGFSIADLAARAKTRGITLGSNR
IVVHHQITREACEDLVALVAELKDEYKDRPKKEIDQEQNRLYAEGVYSRPIEPPIARLGT
SYGKNQ