Protein Info for mRNA_7828 in Rhodosporidium toruloides IFO0880

Name: 16196
Annotation: K01940 argG, ASS1 argininosuccinate synthase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR00032: argininosuccinate synthase
  • amino acids 12 to 421 (410 residues), 497.7 bits, E=1.5e-153
• PF00764: Arginosuc_synth
  • amino acids 15 to 419 (405 residues), 504.6 bits, E=1.2e-155

Best Hits

KEGG orthology group: K01940, argininosuccinate synthase [EC: 6.3.4.5] (inferred from 72% identity to cci:CC1G_05760)

Predicted SEED Role

"Argininosuccinate synthase (EC 6.3.4.5)" in subsystem Arginine Biosynthesis extended (EC 6.3.4.5)

MetaCyc Pathways

• L-arginine biosynthesis II (acetyl cycle) (9/9 steps found)
• L-arginine biosynthesis I (via L-ornithine) (8/9 steps found)
• urea cycle (5/5 steps found)
• superpathway of L-citrulline metabolism (10/12 steps found)
• superpathway of arginine and polyamine biosynthesis (13/17 steps found)
• L-arginine biosynthesis III (via N-acetyl-L-citrulline) (7/9 steps found)
• nitric oxide biosynthesis II (mammals) (2/3 steps found)
• L-arginine biosynthesis IV (archaea) (6/9 steps found)
• canavanine biosynthesis (2/4 steps found)

KEGG Metabolic Maps

• Alanine and aspartate metabolism
• Arginine and proline metabolism
• Urea cycle and metabolism of amino groups

Isozymes

No predicted isozymes

Use Curated BLAST to search for 6.3.4.5

Protein Sequence (442 amino acids)

>mRNA_7828 K01940 argG, ASS1 argininosuccinate synthase (Rhodosporidium toruloides IFO0880)
MSSTVAAGSKGRVLLAYSGGLDTSCILAWLIEQGYEVIAFMADVGQEEDFDAAREKALKI
GAKKFFLADCKKEFVEHLIYPAVQANCIYEGVYLLGTSLARPVIARAMMDVVVTESCQFI
SHGCTGKGNDQVRFELAFYALQPDIKVIAPWRDPVFFERFAGRQALLDFAAEKGIPVFQT
AAKPWSTDENLFHISYEAGILEDPDVTPPADMWKLINGLDKCPTTPERISITFKKGIPVC
LLIHPEGAQPVPSTDGTEITDPVEIFLTLNKLARKHGIGRIDIVENRFIGVKSRGCYESP
GATILRKAHMDLEGLVVDRNVRALRDQFVTTELSKILYNGYWFSPEREFVQSCLQKSQET
VNGRVRLALILGNVIVEGRMSESEALYDAEQVSMDSVTNFDPQATSGFIAIESIRLRKWG
EQRLKKGGNVKPESVYAPKTEI