Protein Info for mRNA_7857 in Rhodosporidium toruloides IFO0880

Name: 16225
Annotation: K00211 TYR1 prephenate dehydrogenase (NADP+)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

Best Hits

Predicted SEED Role

"Prephenate and/or arogenate dehydrogenase (unknown specificity) (EC 1.3.1.12)(EC 1.3.1.43)" in subsystem Chorismate Synthesis or Phenylalanine and Tyrosine Branches from Chorismate (EC 1.3.1.12, EC 1.3.1.43)

MetaCyc Pathways

superpathway of aromatic amino acid biosynthesis (16/18 steps found)
superpathway of L-tyrosine biosynthesis (10/10 steps found)
L-tyrosine biosynthesis I (3/3 steps found)
L-tyrosine biosynthesis III (2/3 steps found)
4-hydroxy-3-prenylbenzoate biosynthesis (1/4 steps found)
novobiocin biosynthesis (2/19 steps found)
superpathway of chorismate metabolism (28/59 steps found)

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.3.1.12 or 1.3.1.43

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (463 amino acids)

>mRNA_7857 K00211 TYR1 prephenate dehydrogenase (NADP+) (Rhodosporidium toruloides IFO0880)
MPALPPVAEAVIGLIGMGEMGKMYAERLSKGGQCKKINVCDLPERYDQLVEYCKGASFAL
LLCLGLHLALITPSAGKDKLVPLRDGHLVSRESDFIIYSVEAAYVDKVVAQYGPSTKVGA
IVSGQTSVKAPERAAFEKHLPADVHIVSIHSLHGPTVPSDGQALIVIQHRADNEHVRFVK
EVLAPLNSRYVDLSYDEHDEVTANTQAVTHAAFLSMGTAWRCTGQFPWELGRYIGGIEVV
KINITLRIYAAKWHVYAGLAILNPTAQKQIHQFAQSASDLFKLMVQNNEAELRRRVLAAR
DFVFGSTDGSSPDAQPAPILLSDSVLDRFAIGDPSPNQPAPPPNSHLALLAMVDCWHQLR
IRPFVHLALAATPVFRFWIGVAEYLFRDEERLEAAIKAAGRLGGDGIAFSSDDAEFVIAA
RGWSDTVRYGSFEAYKQRFDETRMFFEPRFECVRNFFLFTRAL