Protein Info for mRNA_7907 in Rhodosporidium toruloides IFO0880

Name: 16275
Annotation: K14951 ATP13A3_4_5 cation-transporting ATPase 13A3/4/5

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1200 1300 1400 1500 1600 1700 1839 transmembrane" amino acids 283 to 302 (20 residues), see Phobius details amino acids 475 to 492 (18 residues), see Phobius details amino acids 498 to 515 (18 residues), see Phobius details amino acids 693 to 717 (25 residues), see Phobius details amino acids 719 to 723 (5 residues), see Phobius details amino acids 728 to 748 (21 residues), see Phobius details amino acids 1248 to 1269 (22 residues), see Phobius details amino acids 1275 to 1294 (20 residues), see Phobius details amino acids 1315 to 1337 (23 residues), see Phobius details amino acids 1362 to 1381 (20 residues), see Phobius details amino acids 1393 to 1411 (19 residues), see Phobius details amino acids 1432 to 1457 (26 residues), see Phobius details PF12409: P5-ATPase" amino acids 266 to 414 (149 residues), 68.6 bits, see alignment E=1.5e-22 TIGR01657: P-type ATPase of unknown pump specificity (type V)" amino acids 275 to 1436 (1162 residues), 1050.1 bits, see alignment E=0 PF00122: E1-E2_ATPase" amino acids 542 to 755 (214 residues), 94.5 bits, see alignment E=1.5e-30 PF00702: Hydrolase" amino acids 772 to 1070 (299 residues), 31.1 bits, see alignment E=7.2e-11 PF13246: Cation_ATPase" amino acids 930 to 972 (43 residues), 23 bits, see alignment (E = 1.8e-08) TIGR01494: HAD ATPase, P-type, family IC" amino acids 1164 to 1271 (108 residues), 94.6 bits, see alignment 7.2e-31 PF00762: Ferrochelatase" amino acids 1490 to 1796 (307 residues), 310.8 bits, see alignment E=2.5e-96 TIGR00109: ferrochelatase" amino acids 1502 to 1795 (294 residues), 292.4 bits, see alignment E=7.3e-91

Best Hits

Predicted SEED Role

"Ferrochelatase, protoheme ferro-lyase (EC 4.99.1.1)" in subsystem Experimental tye or Heme and Siroheme Biosynthesis (EC 4.99.1.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 4.99.1.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1839 amino acids)

>mRNA_7907 K14951 ATP13A3_4_5 cation-transporting ATPase 13A3/4/5 (Rhodosporidium toruloides IFO0880)
MADPPDSAGPSTPPNADQRPAGALTSILKQTSYDPSSPAGPQFFPSETVPASSDQPLQQD
EDPEAAGQEDDYDDPDGALWSGPAAASVPTTTSAVESESEDERVGFFEGLSNVFRGRRAS
SHRPDVSPARSRAGSVRSRQTSRRRGEEDEDAVSVRSESDFAGDDEDPYGPYGSSSESAS
TSSTTSTSSSQDNDGPRRRRTTTGAGGAGLLGLPGGGGNDFFGESRIDFEEVEDDEMSSL
SEETDDGGHGKGPSKPHHQLIYIPDEDLPLRFVGLHISSFKLGLWYAGCVLSLGIVWLVG
RWMPEWWRRANGKMGEFAASQFVVVETYHHPTQILPLQTLRLPAPTPLSTLFPPSVTLPP
AHRDDVSHPSSPSLNGISNGNGATARKKAQLAAAGHTVDEIQFVDYRYYRFILHPGDGMF
RMVREWKDPTWTSLPQLRRGLSTASSQLALRTTLFDSNAIEIEAKSIGTLLMDEVLHPFY
IFQIVSILLWAIDDYFYYAFAIGVISIVSIVSTLLETRAVRPIRPLKNVQRMQEMSRFSC
PVRVLRDSEWMMADSSTLVPGDLVDLSEPSLHTFPADLILLSGDAIVNESMLTGESVPVS
KVPIEPEFVPLVSSPGPEIAPELARYVVFNGTKIIRIRKTAPSVAQGGKPGADLEAVAMV
VRTGFNTTKGALVRSMLFPKPFGFAFYRDSFRFIGVLAGVAVIGFLASAVNFIKLGIAWS
VILIRAGDLITIVVPPALPATMAIGTSFSIQRLRKMGIFCISPTRVNIGGKVNIVCFDKT
GTLTEEGLDVLGVRSVVRSTNVFTELHRDPDDVPIFGAADAKTPLLHALTTCHALKVVNG
EVIGDPLDLRMFEFTGWTLEEGKEGVGKKSADSASTRRKKATDTGSSSKVPERAQTLVQT
VVRPPGGESFKLEDALKAGSKHAHFLELGVLRTFDFVSSLRRMSVLVKKLKSNSVEACVK
GAPEVMIDICDKSTLPEDYEVVLADYTRHGYRVIALAGKSMPGLTWIKAQRLKREAVESD
LRFLGLVIFENKLKPGTTPAIATFRQAHLPTRMVTGDNVRTAISVGRECGMIQPLARVYL
PTFVKGSSTTPRSQIEWNDVEDETKTLDPYSLKEIVERDDSSVFSGYSSERREYHLAVTG
DVFRWMMDFGALETLQRMLVKGVIFARMSPDEKHELVERLQSLGYTVGFCGDGANDCGAL
KAADVGLSLSEAEASVAAPFTSRQPDIRCFLEVIKEGRASLVTSFSCFKFMALYSLIQFT
TVSLLYSIASTLGDFQFLYIDLFLILPIAVTMGRTEPFPRIHPKRPTANLISKKVLTSLV
GQIVLTSGFQLFTFLWIRSRDWYSPPIIDPDQLDIVSYENTSLFLLSSFQYILVAAVFCV
GPPYRKPIYSNRWLVAALLALSTFSLYTLFMPTSSPVFALLQFIALPHEFHLELLLIILA
NVALSWALEHFAAMRIARWIGDMQRRWRRMRGRRKESGKAYKAISRLRRRSRELTPDRAD
LIPLPFQSTIAPLIAKRRTPKIEKQYEAIGGGSPILRWTRVQGEGMAKLLDELSPETAPH
KAYVAFRYANPLTETCLEEMKRDGVKRAIAFTQYPQYSCSTTGSSLNEMWKQSVDLGKGK
GQEGRDEIQWSVIDRWGVHEGFVDAVARNIEASLQTYPSEVRDSVVLLFSAHSLPMSVVN
RGDPYPPEVGASVSAIMARLGNRNPYRLVWQSQVGPSAWLGPQTSDAIKGLAKKGHNDML
LVPVAFTSDHIETLFELDLEYLEEAKELGLTGVKRVESLNDSPYFIRALADIAAAHIKSG
KTVSAQLGLRCPGCTNEKCGKQKAWFKSFADKAQQQVSA