Protein Info for mRNA_8224 in Rhodosporidium toruloides IFO0880
Name: 16592
Annotation: K00948 PRPS, prsA ribose-phosphate pyrophosphokinase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Predicted SEED Role
"Ribose-phosphate pyrophosphokinase (EC 2.7.6.1)" in subsystem De Novo Purine Biosynthesis or Pentose phosphate pathway (EC 2.7.6.1)
MetaCyc Pathways
- superpathway of histidine, purine, and pyrimidine biosynthesis (38/46 steps found)
- PRPP biosynthesis (1/1 steps found)
KEGG Metabolic Maps
- Biosynthesis of alkaloids derived from histidine and purine
- Biosynthesis of plant hormones
- Pentose phosphate pathway
- Purine metabolism
Isozymes
Compare fitness of predicted isozymes for: 2.7.6.1
Use Curated BLAST to search for 2.7.6.1
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (375 amino acids)
>mRNA_8224 K00948 PRPS, prsA ribose-phosphate pyrophosphokinase (Rhodosporidium toruloides IFO0880) MPNGSSIKLLTGNSHPELAQMVAQRLGIPLTPCTVKKFSDNETSVQIGESVREEDVFIIQ TGFNPSPHPFGAKARHYGTDSDPEVTRPGTPLPPLANRNDLNSRPSSPSKPSPAPANDPN DLLMELLIMISACKTASAKRITAVIPCFPYARMDRKDKSRSPITAKLVANMLQIAGCDHV ITMDLHASQIQGFFQVPVDNLWTEPSMVRWVKENIDDWHNAIIVSPDAGGAKRATNLADR LDCDFALINRNRSKGDGPDSEGKMELLVGDVKNKTAILIDDMADTGGTIKLATQTLVEKG AKEVYALVSHGLLSGRSMEELAKMPLVKVVVSNTVCQTEHFKKAQGKLEVMDISPVLAES IRRTHNGESISLLFK