Protein Info for mRNA_8278 in Rhodosporidium toruloides IFO0880

Name: 16646
Annotation: K16330 K16330 pseudouridylate synthase / pseudouridine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 779 PF04227: Indigoidine_A" amino acids 44 to 346 (303 residues), 369.4 bits, see alignment E=1.4e-114 PF00294: PfkB" amino acids 401 to 603 (203 residues), 30.6 bits, see alignment E=2.3e-11

Best Hits

Predicted SEED Role

"Indigoidine synthase A-like protein, uncharacterized enzyme involved in pigment biosynthesis"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (779 amino acids)

>mRNA_8278 K16330 K16330 pseudouridylate synthase / pseudouridine kinase (Rhodosporidium toruloides IFO0880)
MLSRTALRTAARRPRARPFFTTSSPSTWSGPRSLAGLPIDIAPEVAQAKAEGRAIVALES
TLVTHGLPPPHSASLPKDCEAILRSQGVTPATIAILNGRIKVGLQEKDLVHLAERGWEAR
KDKTVAEKMWKVGRRELAAAVVKRLDGGTTVSGTMAVAHLAGIKIFSTGGIGGVHRGAET
SFDISSDLISLSDTPVAVVCAGSKSILDIGLTLEYLEAHAVPVAVYKTADREWPAFYTAE
SGFKAPMNMESAREVAETIVMTDKLGLPSSLLLGNPIPAEYHDVGEELQRAVDQAVAESV
ENGMAKSGKQVTPWLLARVAELSRGKSLENKALIRNNVKVGGEVALEYARLLKESSPASS
AFMPALSPSASAAAPAAPTAATAIDTPSPPASLIVAGVLAVDITMHPSSSSPLQTTAPGT
VSLTLGGVAGNVAGAAHSLLSGQSDDDVLLVAPVADDLLGGVAKSGLAKRGMRDDGLIST
STSGTATCGILLDEKGELVGGIADMGIATELSGKKIVERMQSASPAVVCFDGNLSQDAIA
DIVTHCLERSIPTFFEPTSNAKALQLLRALEKKPHLASLLPATSSYVSFSAPNIHELSHL
YQHIAFSDHPLYNSAPWFDHVTVPAHDLSLRLPKWIIDEGVAQMAVRLISTSLFGSLLIK
SGSRGVLVVQRVSGVDNVAAWSSLPSRKGTVVVRSTQPSDAVVLRHYPALELDERQVGTV
TGAGDNLAGAILAGLVRRLSPFVPDELDRLANLGQRAAVATLQSKEAVGDHSSLSALLP