Protein Info for mRNA_8465 in Rhodosporidium toruloides IFO0880

Name: 16833
Annotation: K00293 LYS9 saccharopine dehydrogenase (NADP+, L-glutamate forming)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF17284: Spermine_synt_N
  • amino acids 13 to 67 (55 residues), 76.9 bits, 2.3e-25
• TIGR00417: spermidine synthase
  • amino acids 14 to 280 (267 residues), 340.7 bits, E=2.9e-106
• PF01564: Spermine_synth
  • amino acids 70 to 246 (177 residues), 221.6 bits, E=1.5e-69
• PF03435: Sacchrp_dh_NADP
  • amino acids 302 to 418 (117 residues), 83.8 bits, E=3.3e-27
• PF16653: Sacchrp_dh_C
  • amino acids 422 to 741 (320 residues), 296.7 bits, E=6.8e-92

Best Hits

KEGG orthology group: K00797, spermidine synthase [EC: 2.5.1.16] (inferred from 65% identity to cci:CC1G_05582)

Predicted SEED Role

"Spermidine synthase (EC 2.5.1.16)" in subsystem Polyamine Metabolism (EC 2.5.1.16)

MetaCyc Pathways

• superpathway of arginine and polyamine biosynthesis (13/17 steps found)
• spermidine biosynthesis I (2/2 steps found)
• superpathway of polyamine biosynthesis I (5/8 steps found)
• L-methionine salvage cycle III (7/11 steps found)
• superpathway of polyamine biosynthesis II (4/8 steps found)
• L-methionine salvage cycle I (bacteria and plants) (6/12 steps found)

KEGG Metabolic Maps

• Arginine and proline metabolism
• Glutathione metabolism
• Methionine metabolism
• Urea cycle and metabolism of amino groups
• beta-Alanine metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.5.1.16

Protein Sequence (750 amino acids)

>mRNA_8465 K00293 LYS9 saccharopine dehydrogenase (NADP+, L-glutamate forming) (Rhodosporidium toruloides IFO0880)
MAAELSHPLIVDGWFREISEQWPGQAMTLRVKKVLHTEKSLYQDVLVFESTDHGNVLVLD
GAIQCVERDEFSYQEMIAHLPLASHPNPEKVLVIGGGDGGVLREVLKHPSVKSATLCDID
EAVPRVSKQFLPHMAAGFNDPRVTVFIGDGFKFLDDKKNEFDVIITDSSDPVGPANSLFQ
KPYFQLLKESLREGGTISTQGECVWLHLPLINDLMSMSRTLFPKAEFGWTSIPTYPSGTI
GFVVATLDGKRDLRTPLRDIQGCRYWSKAIHRQAFTLPAFAQAVVDKSLKPAAPANAQPK
KVLLLGSGFVAQPAAEYVLRRAENSLVVGCRTLATAQQFVESLPRPATAIAVDSSDEASL
DKAVADCDLVISLIPYTQHANVIKSAIKHKKDVVTTSYVSPAMKALHDEAVAAGITVLNE
IGLDPGIDHLYAVKTIDEVHQAGGKVKGFLSYCGGLPAPSAADNPLGYKFSWSSRGVLLA
LLNSAKLYSKGQLVEIDGKDLMKHAKPYYINPAFAFVAYPNRDSTPFREFYNIPEAETVV
RGTLRYQGFPEFIKALVDIGFLNESPVEYLAKGAQALPWAEVTQRALGAQAADEASLIAA
VKGKTSFPSAEEEERIISGLRWIGIFSNEPVSNRGSLLDTLCATLEAKMQYEKGERDMVM
LQHRFEVEKADGTQEIRTSTLLEYGAPTGSDGPSFMAVSVGRTCGVAVQLVLDGQIKQKG
VFAPYTRDVVDPLLAALEAEGFYKMVEKVQ