Protein Info for mRNA_67 in Rhodosporidium toruloides IFO0880

Name: 8435
Annotation: K05864 PPID, CYPD peptidyl-prolyl isomerase D

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 374 PF00160: Pro_isomerase" amino acids 12 to 169 (158 residues), 157.6 bits, see alignment E=1.6e-50

Best Hits

Swiss-Prot: 45% identical to PPID_CANGA: Peptidyl-prolyl cis-trans isomerase D (CPR6) from Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)

Predicted SEED Role

"Peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8)" in subsystem Queuosine-Archaeosine Biosynthesis (EC 5.2.1.8)

Isozymes

Compare fitness of predicted isozymes for: 5.2.1.8

Use Curated BLAST to search for 5.2.1.8

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (374 amino acids)

>mRNA_67 K05864 PPID, CYPD peptidyl-prolyl isomerase D (Rhodosporidium toruloides IFO0880)
MPNPRVYFDVSIQGHSAGRIVMELFADVVPKTAENFRALTTGEKGVGKAGKPLSYKGSKF
HRVIRKFMIQGGDFTAGNGTGGESIYGEKFGDENFDLKHDKPFLLSMANAGPGTNGSQFF
ITTVPTPHLDGKHVVFGRVLHGRSVVRLIEESPVNGDSPAEEILIADCGELAEGEDGVMA
DEFADGHEEYPSDDESDINDPKTALKVATEIKERGTDLFKKGNFEQAQKKYIKALRYLDR
HLDLQARDLELEGQFATLRLSILLNSSLTALKDPGTTSAQLGVKQATRALSLDADPEEHP
MHKKLTDAEKAKALYRRAMASVVLKEENEAIADLELASKLQPEDGGIKAQLNAAKKRVED
RKAKARQAYAKMFN