Protein Info for mRNA_75 in Rhodosporidium toruloides IFO0880
Name: 8443
Annotation: K00606 panB 3-methyl-2-oxobutanoate hydroxymethyltransferase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Predicted SEED Role
"3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11)" in subsystem Coenzyme A Biosynthesis (EC 2.1.2.11)
MetaCyc Pathways
- phosphopantothenate biosynthesis I (4/4 steps found)
- superpathway of coenzyme A biosynthesis I (bacteria) (7/9 steps found)
- phosphopantothenate biosynthesis III (archaea) (2/4 steps found)
- superpathway of coenzyme A biosynthesis II (plants) (5/10 steps found)
KEGG Metabolic Maps
Isozymes
No predicted isozymesUse Curated BLAST to search for 2.1.2.11
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (425 amino acids)
>mRNA_75 K00606 panB 3-methyl-2-oxobutanoate hydroxymethyltransferase (Rhodosporidium toruloides IFO0880) MEWIQTPCQLLSLDRLTLTLANTAVRARLSLDMSTGSVARCFTHALRTASDWAAPVASSS RLLSPARAMPTRAFAGGQRILGHACACCRGQKRAYSSYPTERPGAGAFAPRRKRTIMDFN SLKKKKVPVTMLTAHDYPSARFIESIAPPAPAPGAVPAPAGSSSSAAPRGIDIALVGDSL AMVACGYPSTNYLTLDEMLYHCRSVARGCTTSFLVADLPFGSFSASIEDGVRAAVRLIQE GHMDAVKIEGGPEIVPLIRRLTEVGIPVMAHVGLTPQRQAALSGYRVQGKTVSSAVKVWE DACAVQDAGAFAVVLEAVPSKLAAWVTERLRIPTIGIGAGAGCDGQVLVQLDMLGVDSDL GAGGKGPRFLKKYADVGERAREAVRSYVDEVRRREFPTEGEHTYPIEDKAWEGFLEAVKE TEREA