Protein Info for mRNA_112 in Rhodosporidium toruloides IFO0880

Name: 8480
Annotation: K10899 RECQL ATP-dependent DNA helicase Q1

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 863 TIGR00614: ATP-dependent DNA helicase, RecQ family" amino acids 185 to 655 (471 residues), 385.1 bits, see alignment E=2.5e-119 PF04851: ResIII" amino acids 189 to 371 (183 residues), 30.6 bits, see alignment E=6.9e-11 PF00270: DEAD" amino acids 192 to 375 (184 residues), 63.4 bits, see alignment E=4.7e-21 PF00271: Helicase_C" amino acids 430 to 540 (111 residues), 48.4 bits, see alignment E=2.1e-16 PF16124: RecQ_Zn_bind" amino acids 553 to 621 (69 residues), 39.1 bits, see alignment E=2e-13

Best Hits

Predicted SEED Role

"ATP-dependent DNA helicase RecQ" in subsystem DNA-replication or DNA repair, bacterial RecFOR pathway

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (863 amino acids)

>mRNA_112 K10899 RECQL ATP-dependent DNA helicase Q1 (Rhodosporidium toruloides IFO0880)
MPSRFADDNLQPLAGPSNASARPQNASSVRSLDLPFVDLDNPPRKKQRVSVEREAVSERM
AGGAKGKEAEVMVLEDDDFDEAMQEEWEGDWEDGEADGSAEEQEKLQQLEAELASLDNQI
RELQRLRNEVRTERDTVKVTIASRKSSAPKAKSAAPSRPSAGAVDYTSKRFSWSDEAERL
AGDIWGVKKWRPGQEGAINATLDGREVVAVLPTGGGKSLIFQIPALLSKGTTIVITPLIS
LMSDQVHNLHARGVAAEMIHASTSQAEIKEIMQRMLGTVGSKGKGKKAAAAMEQAEEVKL
VYVTPERIEKSKTFVNTLQKMYDAGLLARFVIDEAHCVSMQGHDYRTSYLSLQRLKVLFP
STPILAVTATAPQTVVADMLKILTLPANLSPGNAALPKTTVLFTAPLYRPNLRYAIVPKP
SSAQTALDAIVDWILENRKGSTGIIYTLSRADSENLTKGINGHERAKGKLRAAFYHAYLE
DAEKQRVHEMWMSGKIQVVVATSASFGLGIDNPNVRFVIHHSLPKSLANYQQESGRAGRD
GEPADCVTFWRAADASRLSSLTYETFHTGGKDKLYEVVRFAEDKKTCRKILFGRYFRNSY
DSSVNTEEDSDTPCEHCDNCLRDPATVSSIDISLQAYRALRIISSATSQRGTLTLPQAAD
LVRGLGGGSFSTQEAKGKGKGKVDVQVVAGEKVTLSKDQTEQMLLQLLVDGFLKEEFHAT
AYAVNSYLHPASKALRFTRLSPDDVDSSNLPLNLTMDVLVSAGSKRKSGATQSDGRAPKK
SRSKKAAPVALETDDESETEFRQTVRGGKSQDDFNVDEDELEAWESALGAEPSSDAALDE
DGWASVKTSRKASAGGVDVLELD