Protein Info for mRNA_115 in Rhodosporidium toruloides IFO0880

Name: 8483
Annotation: K14950 ATP13A1 cation-transporting ATPase 13A1

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1228 transmembrane" amino acids 30 to 50 (21 residues), see Phobius details amino acids 62 to 81 (20 residues), see Phobius details amino acids 202 to 222 (21 residues), see Phobius details amino acids 228 to 248 (21 residues), see Phobius details amino acids 373 to 395 (23 residues), see Phobius details amino acids 407 to 427 (21 residues), see Phobius details amino acids 439 to 455 (17 residues), see Phobius details amino acids 982 to 1002 (21 residues), see Phobius details amino acids 1012 to 1031 (20 residues), see Phobius details amino acids 1046 to 1069 (24 residues), see Phobius details amino acids 1098 to 1117 (20 residues), see Phobius details amino acids 1129 to 1149 (21 residues), see Phobius details amino acids 1168 to 1191 (24 residues), see Phobius details TIGR01657: P-type ATPase of unknown pump specificity (type V)" amino acids 52 to 1170 (1119 residues), 1089.8 bits, see alignment E=0 PF00122: E1-E2_ATPase" amino acids 268 to 472 (205 residues), 74.8 bits, see alignment E=6.8e-25 TIGR01494: HAD ATPase, P-type, family IC" amino acids 401 to 513 (113 residues), 64.9 bits, see alignment E=4.9e-22 PF00702: Hydrolase" amino acids 490 to 729 (240 residues), 38.3 bits, see alignment E=1.8e-13

Best Hits

Predicted SEED Role

"Lead, cadmium, zinc and mercury transporting ATPase (EC 3.6.3.3) (EC 3.6.3.5); Copper-translocating P-type ATPase (EC 3.6.3.4)" (EC 3.6.3.3, EC 3.6.3.4, EC 3.6.3.5)

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.3, 3.6.3.4, 3.6.3.5

Use Curated BLAST to search for 3.6.3.3 or 3.6.3.4 or 3.6.3.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1228 amino acids)

>mRNA_115 K14950 ATP13A1 cation-transporting ATPase 13A1 (Rhodosporidium toruloides IFO0880)
MASLRFPGGRVAVTSPDIASLQLVNPLPAWARVYVLPWLVAYPLAYHAFYNRYDDWIRSI
EWTFLLCIVLFGGHALSFLFTRWSMQFRARGEARHVDDLATAQQVMVLPKLHRGKPEMCK
IHRTQRPGQPDLIYFSYQRDKYMYNHSTSTFGRVSYPCDGAPALSTLQASKGLTTATAIE
QARTDYGKNEFDIPVPTFGELFAEHAVAPFFVFQLFCTALWLFDDYWYYSLFTLFMLVVF
ECVTIFQRLRTVSEFRSMSIKPYGIMTRRENKWIEVQTDELLPGDIVSIVRTKEDSGVPC
DLLLLRGSCIVNEAMLSGESTPLLKESVELRPGDDKLDMDGVDRNSVLFGGTKVLQATGV
DPKDKMAAPDHGCLAIVLRTGFGTSQGQLIRTMIFSTETVTANNLESFLFIAFLLVFALA
ASAYVWIKGLEQDRKRSKLLLDCVIIITSVVPPELPMELSMAVNASLVALSKYSIFCTEP
FRIPYAGRVDICCFDKTGTITGEDLVVEGVAGVDSNDRKTLVPVQDTSLETTLTLASAHA
LVLLDDGIVGDPMEKATLDSLKWKLSNGDKLTPTDDAAHKKDGVSVVVRRRFQFSSQLKR
MSTISLVQTGPSSVRTLVAVKGAPETLKSMYTSVPEEYEATYKWYAQRGSRVLALGYKWI
DGMNKNETTTIARENVESQLTFAGFLVFHCPLKADAVQTLKDLADASHRCVMITGDNPLT
AVHVARDVEIVDRDVLILDLKEGAQNETELTWRSPDESIVIPVNPADPIDTSLFDKYDIC
MTGSALKQYVDRKESWHHLVQNTWVYARVSPAQKEFILTTLKSLGYVTLMAGDGTNDVGA
LKQANIGVALLNGTEEDLKAILEHQKKERVKKVYEQQLRITSRFGQPPPPVPPLIADLFP
DAVKAQQEAAKNVTSDRQKGKVNKFDVSAITEQLSNLEDDQDVPQIKLGDASVAAPFTSK
LANVAAISHIIRQGRCTLVATIQMYKILALNCLISAYALSVQYLQGIKSGDYQMTITGIL
LSVCFMCISRARPVDKLSKERPLASIFNAYVVVSILVQFAIHVASFIYVTNLSEQYEPRI
GMDVDLDAKFSPNLLNSAVYLISLSQQISTFAINFQGRPFRENISENSALYYGLLGVAAV
AFSGATDFVPEFNRWLQLVDMEWSFRTRLCAAMAIDYGGAWIVDIVLKALWANTQPKPLI
TKGSERREERREAQKRAQELAEEAKKTE